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Recombinant Mouse Itgb1 protein, His-tagged

Cat.No. : Itgb1-15M
Product Overview : Recombinant Mouse Itgb1(Val128~Asn399) fused with His tag at N-terminal was expressed in E. coli.
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Description : Itgb1 played an important role in many functions.
Source : E. coli
Species : Mouse
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300
Molecular Mass : 32.5kDa
Protein length : Val454~Ile714
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others.
Gene Name : Itgb1 integrin beta 1 (fibronectin receptor beta) [ Mus musculus ]
Official Symbol : Itgb1
Synonyms : ITGB1; integrin beta 1 (fibronectin receptor beta); integrin beta-1; VLA-4 subunit beta; fibronectin receptor subunit beta; CD29; Fnrb; gpIIa; Gm9863; AA409975; AA960159; 4633401G24Rik; ENSMUSG00000051907;
Gene ID : 16412
mRNA Refseq : NM_010578
Protein Refseq : NP_034708
UniProt ID : P09055
Chromosome Location : 8; 8 E2
Pathway : Adaptive Immune System, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem;
Function : actin binding; alpha-actinin binding; binding; collagen binding; fibronectin binding; glycoprotein binding; integrin binding; integrin binding; kinase binding; laminin binding; peptide binding; protease binding; protein binding; protein complex binding; protein domain specific binding; protein heterodimerization activity; protein kinase binding; receptor activity; receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Are there have therapeutic strategies for ITGB1 protein? 08/20/2023

Therapeutic strategies for ITGB1 protein may include inhibiting its expression, blocking its binding to ligands, or regulating its associated signal transduction pathways. These methods may have potential applications in cancer treatment.

What are the interactions between ITGB1 protein and other proteins? 04/14/2023

The ITGB1 protein can interact with a variety of other proteins, including ligands, proteins in signal transduction pathways, etc. These interactions enable it to regulate processes such as cell growth, differentiation, and apoptosis.

How about the specific role of ITGB1 protein in cancer? 04/18/2022

In cancer, ITGB1 protein may play a role by promoting processes such as the proliferation, migration and invasion of tumor cells, thus promoting the occurrence and development of tumors. It could be a potential target for cancer treatment.

Which is the main function of ITGB1 protein in cells? 03/31/2022

The main function of ITGB1 protein in cells is to act as a cell adhesion receptor, participate in the interaction between cells and extracellular matrix, and play an important role in cell migration and signal transduction.

What is the relationship between ITGB1 protein structure and function? 12/05/2020

The structure of the ITGB1 protein determines its ability and stability to bind to ligands. The study of its structure can help us understand its function and mechanism of action.

How about the association between ITGB1 protein expression level and disease? 02/23/2020

Recent literature has shown that the expression level of ITGB1 protein is related to the occurrence and development of a variety of diseases, including cancer, cardiovascular diseases, neurodegenerative diseases, etc.

Customer Reviews (3)

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Reviews
06/24/2023

    The range of applications for ITGB1 is impressive, and it can play an important role in any field.

    04/19/2023

      ITGB1 performed very well in Western blot, with clear bands and improved experimental accuracy.

      05/29/2021

        ITGB1 has a strong desensitization potential for specific allergens.

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