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Active Recombinant Mouse Loxl2 protein, His-tagged

Cat.No. : Loxl2-262M
Product Overview : Recombinant Mouse Loxl2 protein(NP_201582.2)(Met1-Gln776), fused with His tag, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Mouse
Tag : His
Form : Lyophilized from sterile 20 mM MES, 150 mM NaCl, pH 6.5.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Bio-activity : Measured by its ability to produce hydrogen peroxide during the oxidation of benzylamine.The specific activity is > 3pmoles/min/μg.
Molecular Mass : The recombinant mouse Loxl2 consists 762 amino acids and predicts a molecular mass of 85.9 kDa.
Protein Length : Met1-Gln776
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 80 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : Loxl2 lysyl oxidase-like 2 [ Mus musculus ]
Official Symbol : Loxl2
Synonyms : LOXL2; lysyl oxidase-like 2; lysyl oxidase homolog 2; lysyl oxidase-like protein 2; 1110004B06Rik; 4930526G11Rik; 9430067E15Rik; MGC102220;
Gene ID : 94352
mRNA Refseq : NM_033325
Protein Refseq : NP_201582

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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In what ways does LOXL2 impact tissue elasticity, and how is this relevant in clinical applications? 06/14/2021

LOXL2 promotes the cross-linking of elastin fibers, affecting tissue elasticity. Understanding these mechanisms can have implications in diseases where tissue flexibility is crucial, such as in cardiovascular conditions.

How does LOXL2 influence wound healing, and can it be targeted for therapeutic interventions? 03/04/2021

LOXL2 is involved in tissue repair and wound healing by modulating the extracellular matrix. Targeting LOXL2 may offer therapeutic opportunities to enhance or control the wound healing process.

Are there diagnostic applications of LOXL2 in clinical settings? 05/03/2020

Elevated levels of LOXL2 have been associated with certain diseases. Measuring LOXL2 levels can potentially serve as a diagnostic marker for conditions such as liver fibrosis and certain cancers.

Are there ongoing clinical trials targeting LOXL2 for therapeutic purposes? 06/08/2019

Yes, several clinical trials are exploring the potential of LOXL2 inhibitors in treating fibrosis and cancer. These trials aim to validate the efficacy and safety of targeting LOXL2 in clinical settings.

How does LOXL2 contribute to the clinical understanding of fibrosis? 06/28/2017

LOXL2 is implicated in fibrosis as it plays a key role in collagen cross-linking, influencing tissue stiffness and architecture, making it a potential target for anti-fibrotic therapies.

Customer Reviews (3)

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Reviews
06/20/2022

    This protein exhibits outstanding performance in ELISA, providing accurate and reliable results in detecting and quantifying specific antigens.

    01/16/2022

      Its high sensitivity ensures the detection of even low abundance targets, making it a valuable tool in immunoassays.

      03/23/2016

        Its stability and compatibility with electron microscopy techniques make it an excellent choice for studying protein structures at high resolution.

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