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Recombinant Mouse Mesdc2 protein, His-tagged

Cat.No. : Mesdc2-199M
Product Overview : Recombinant mouse MESDC2, fused to His-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques.
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  • Gene Information
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Description : MESDC2 also known as LDLR chaperone MESD. This protein is specialized chaperone for low-density lipoprotein receptor-related protein 5 and LRP6. MESDC2 binds to mature LRP6 on the cell surface and blocks the binding of Wnt antagonist Dickkopf-1 to LRP6. Furthermore, MESDC2 plays an essential role in NMJ formation by promoting Lrp4 maturation.
Source : E.coli
Species : Mouse
Tag : His
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol
Molecular Mass : 24.4kDa (218aa)
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSADTPGEA TPPPRKKKDI RDYNDADMAR LLEQWEKDDD IEEGDLPEHK RPSAPIDFSK LDPGKPESILKMTKKGKTLM MFVTVSGNPT EKETEEITSL WQGSLFNANY DVQRFIVGSD RAIFMLRDGS YAWEIKDFLV SQDRCAEVTL EGQMYPGKGGGSKEKNKTKP EKAKKKEGDP KPRASKEDNR AGSRRE?
Purity : > 90% by SDS - PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1mg/ml (determined by Absorbance at 280nm)
Gene Name : Mesdc2 mesoderm development candidate 2 [ Mus musculus ]
Official Symbol : Mesdc2
Synonyms : MESDC2; mesoderm development candidate 2; LDLR chaperone MESD; msd; mesd; AW537813; mKIAA0081; 2210015O11Rik; MGC25959;
Gene ID : 67943
mRNA Refseq : NM_023403
Protein Refseq : NP_075892
Function : low-density lipoprotein particle receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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