Recombinant Mouse Mmp9 protein, His-tagged

• Cat.No.: Mmp9-2793M
• Product Overview: Recombinant Mouse Mmp9 aa. (Ser225~Asp390 (Accession # P41245)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme that degrades collagens of type IV, V and XI, and elastin. Mice lacking the encoded protein exhibit an abnormal pattern of skeletal growth plate vascularization and ossification, reduced keratinocyte hyperproliferation at all neoplastic stages, a decreased incidence of invasive tumors, and resistance to experimental autoimmune encephalomyelitis.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 19.9kDa
• Protein length: Ser225~Asp390 (Accession # P41245)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.2.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Mmp9 matrix metallopeptidase 9 [ Mus musculus (house mouse) ]
• Official Symbol: Mmp9
• Synonyms: Clg4b; Gel B; MMP-9; B/MMP9; AW743869; pro-MMP-9; 92 kDa gelatinase; 92 kDa type IV collagenase; 92kD gelatinase; 92kD type IV collagenase; collagenase type IVB; gelatinase B; matrix metalloproteinase-9
• Gene ID: 17395
• mRNA Refseq: NM_013599.4
• Protein Refseq: NP_038627.1
• UniProt ID: P41245