Recombinant Mouse Tfrc protein, His-tagged

• Cat.No.: Tfrc-1567M
• Product Overview: Recombinant Mouse Tfrc aa. (Arg572~Trp757) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 29kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Arg572~Trp757
• Endotoxin: <1.0EU per 1µg (determined by the LAL method).
• Purity: >92%
• Characteristic: The isoelectric point is 6.5.
• Applications: SDS-PAGE; WB; ELISA; IP; CoIP; ReporterAssays; Purification; Amine Reactive Labeling.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Concentration: 200µg/mL
• Storage buffer: PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300.
• Reconstitution: Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Tfrc transferrin receptor [ Mus musculus (house mouse) ]
• Official Symbol: Tfrc
• Synonyms: TR; TFR; p90; CD71; TFR1; Trfr; Mtvr1; 2610028K12Rik; E430033M20Rik; mammary tumor virus receptor 1; transferrin receptor protein 1
• Gene ID: 22042
• mRNA Refseq: NM_011638.4
• Protein Refseq: NP_035768.1
• UniProt ID: Q62351