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Home > Products > Recombinant Proteins > Recombinant Mouse Tnfsf18 protein, Fc-tagged

Recombinant Mouse Tnfsf18 protein, Fc-tagged

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Fc(2)
Flag(4)
His(13)
His/S(3)
N/A(2)
T7 tag(1)
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Cat.No.:
Tnfsf18-19M
Product Overview:
Recombinant Mouse Tnfsf18(Thr 47 - Ser 173) fused with human IgG1 Fc tag at the N-terminus was expressed in HEK293.
Description:
Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
Source:
HEK293
Species:
Mouse
Tag :
Fc
Form:
Lyophilized from 0.22 μm filtered solution in 50 mM Tris,100 mM Glycine,pH7.5. Normally trehalose is added as protectant before lyophilization.
Molecular Mass:
The protein has a calculated MW of 41.4 kDa. As a result of glycosylation, The protein migrates as 45 kDa under reducing (R) condition and 80-100 kDa under non-reducing (NR) condition on SDS-PAGE gel.
Protein length:
Thr 47 - Ser 173
Endotoxin:
Less than 1.0 EU per μg by the LAL method.
Purity:
>95% as determined by SDS-PAGE.
Storage:
For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
No activity loss is observed after storage at:
4-8 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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