Recombinant Mouse Tyrp1 Protein, His-tagged

• Cat.No.: TYRP1-17676M
• Product Overview: Recombinant Mouse TYRP1 Protein with a His tag was expressed in HEK293.

Specification

• Description: Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.
• Source: HEK293
• Species: Mouse
• Tag: His
• Molecular Mass: 52.1 kDa
• AA Sequence: QFPRECANIEALRRGVCCPDLLPSS GPGTDPCGSSSGRGRCVAVIADSRP HSRHYPHDGKDDREAWPLRFFNRTC QCNDNFSGHNCGTCRPGWRGAACNQ KILTVRRNLLDLSPEEKSHFVRALD MAKRTTHPQFVIATRRLEDILGPDG NTPQFENISVYNYFVWTHYYSVKKT FLGTGQESFGDVDFSHEGPAFLTWH RYHLLQLERDMQEMLQEPSFSLPYW NFATGKNVCDVCTDDLMGSRSNFDS TLISPNSVFSQWRVVCESLEEYDTL GTLCNSTEGGPIRRNPAGNVGRPAV QRLPEPQDVTQCLEVRVFDTPPFYS NSTDSFRNTVEGYSAPTGKYDPAVR SLHNLAHLFLNGTGGQTHLSPNDPI FVLLHTFTDAVFDEWLRRYNADIST FPLENAPIGHNRQYNMVPFWPPVTN TEMFVTAPDNLGYAYEVQWPGQEFT VSEHHHHHH
• Purity: > 90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.78 mg/mL
• Storage Buffer: BS, pH 7.4
• Publication:
  A novel mouse strain optimized for chronic human antibody administration (2022)

Gene Information

• Gene Name: Tyrp1 tyrosinase-related protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Tyrp1
• Synonyms: Tyrp1; tyrosinase-related protein 1; b; Oc; TR; Ty; isa; Oca3; TRP1; Tyrp; TRP-1; brown; 5,6-dihydroxyindole-2-carboxylic acid oxidase; DHICA oxidase; brown locus protein; catalase B; iris stromal atrophy; EC 1.14.18.-
• Gene ID: 22178
• mRNA Refseq: NM_031202
• Protein Refseq: NP_112479
• UniProt ID: P07147