Active Recombinant Mouse Wnt3a protein

• Cat.No.: Wnt3a-456M
• Product Overview: Recombinant Mouse Wnt3a(334 amino acid residues) was purified from Cell Culture.

Specification

• Source: Cell Culture
• Species: Mouse
• Bio-activity: The ED50 was determined by its ability to induced alkaline phosphatase production by CCL-226 cells. The expected ED50 for this effect is 0.4-0.6 ng/ml.
• Molecular Mass: Due to glycosylation, the murine Wnt-3a migrates at an apparent molecular weight of approximately 38.0-41.0 kDa by SDS-PAGE analysis under non-reducing conditions.
• AA Sequence: SYPIWWSLA VGPQYSSLS TQPILCASI PGLVPKQLR FCRNYVEIM PSVAEGVKA GIQECQHQF RGRRWNCTT VSNSLAIFG PVLDKATRE SAFVHAIAS AGVAFAVTR SCAEGSAAI CGCSSRLQG SPGEGWKWG GCSEDIEFG GMVSREFAD ARENRPDAR SAMNRHNNE AGRQAIASH MHLKCKCHG LSGSCEVKT CWWSQPDFR TIGDFLKDK YDSASEMVV EKHRESRGW VETLRPRYT YFKVPTERD LVYYEASPN FCEPNPETG SFGTRDRTC NVSSHGIDG CDLLCCGRG HNARTERRR EKCHCVFHW CCYVSCQEC TRVYDVHTC K
• Purity: Above 75% as determined by SDS-PAGE Analysis.

Gene Information

• Gene Name: Wnt3a wingless-related MMTV integration site 3A [ Mus musculus ]
• Official Symbol: Wnt3a
• Synonyms: WNT3A; wingless-related MMTV integration site 3A; protein Wnt-3a; vestigial tail; vt; Wnt-3a
• Gene ID: 22416
• mRNA Refseq: NM_009522
• Protein Refseq: NP_033548
• UniProt ID: P27467
• Chromosome Location: 11 B1.3; 11 37.17 cM
• Pathway: Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; ESC Pluripotency Pathways, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem
• Function: frizzled binding; frizzled-2 binding; protein binding; protein domain specific binding; receptor agonist activity; receptor binding; transcription coactivator activity