Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Rat Ache protein, His-tagged

Cat.No. : Ache-6971R
Product Overview : Recombinant Rat Ache aa. (Gly157~Pro332 (Accession # P37136)) fused with N-terminal His tag was produced in E. coli cells.
  • Specification
  • Gene Information
  • Related Products
Description : Catalyzes the hydrolysis of acetylcholine to choline and acetate; plays a role in neuronal development and synapse formation.
Source : E. coli
Species : Rat
Tag : His
Form : Freeze-dried powder
Molecular Mass : 20 kDa as determined by SDS-PAGE reducing conditions.
Protein length : Gly157~Pro332 (Accession # P37136)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.3.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Ache acetylcholinesterase [ Rattus norvegicus (Norway rat) ]
Official Symbol : Ache
Synonyms : Ache; acetylcholinesterase; acetylcholinesterase; glycolipid-anchored form of acetylcholinesterase
Gene ID : 83817
mRNA Refseq : NM_172009.1
Protein Refseq : NP_742006.1
UniProt ID : P37136

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (8)

Ask a question
When can I receive the product after ordering? 02/08/2023

The time required for different proteins varies, you can pay attention to the information on the product details page, or contact our experts directly.

Can ACHE-3333HFL products change tags? 12/02/2022

Sure. We can customize proteins according to customer needs, including different tags, expression system, protein length, etc.

Why the protein length of ACHE-101H product is 1-351aa? 11/19/2022

Because we can customize proteins of different lengths according to customer needs, please contact us if you are interested in this product.

What is the mechanism by which patients with Alzheimer's disease are treated with acetylcholinesterase inhibitors? 04/26/2022

Patients with Alzheimer disease often receive treatment with acetylcholinesterase inhibitors that mitigate symptoms by hindering ACh turnover.

In which tissues is acetylcholinesterase mainly distributed? 04/14/2021

Acetylcholinesterase is known to be distributed in nervous tissue such as the brainstem, cerebellum, and peripheral and autonomic nervous systems. Skeletal muscle also contains AChE with distribution patterns seemingly related to the type of muscle (fast versus slow twitch) and their specific function. AChE is also present on red blood cell membranes.

Does ACHE only work on terminating neurotransmission? 03/16/2021

Although the primary function of AChE is to terminate neural transmission, investigators have found that AChE also plays a role in neural development. During fetal development, AChE contributes to morphogenesis in addition to its main enzymatic function.

What form does acetylcholinesterase usually exist in? 07/29/2020

Acetylcholinesterase exists as a monomer that often polymerizes into a dimer with a disulfide bond. Along with Van der Waals forces, two dimers may be linked to become tetramers.

What is the role of ACHE? 02/04/2020

The primary role of AChE is to terminate neuronal transmission and signaling between synapses to prevent ACh dispersal and activation of nearby receptors. They are an important component of pesticides and nerve agents.

Customer Reviews (2)

Write a review
Reviews
12/12/2020

    I have already recommended creative biomart products to many colleagues.

    05/09/2019

      Received the product very quickly after placing the order, I am very satisfied.

      Ask a Question for All Ache Products

      Required fields are marked with *

      My Review for All Ache Products

      Required fields are marked with *

      0

      Inquiry Basket

      cartIcon
      logo

      FOLLOW US

      Terms and Conditions        Privacy Policy

      Copyright © 2024 Creative BioMart. All Rights Reserved.

      Contact Us

      • /

      Stay Updated on the Latest Bioscience Trends