Recombinant Rat Ache protein, His-tagged
Cat.No. : | Ache-6972R |
Product Overview : | Recombinant Rat Ache aa. (Gly366~Gly554 (Accession # P37136)) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
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Description : | Catalyzes the hydrolysis of acetylcholine to choline and acetate; plays a role in neuronal development and synapse formation. |
Source : | E. coli |
Species : | Rat |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 23 kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Gly366~Gly554 (Accession # P37136) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 6.3. |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | Ache acetylcholinesterase [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Ache |
Synonyms : | Ache; acetylcholinesterase; acetylcholinesterase; glycolipid-anchored form of acetylcholinesterase |
Gene ID : | 83817 |
mRNA Refseq : | NM_172009.1 |
Protein Refseq : | NP_742006.1 |
UniProt ID : | P37136 |
Products Types
◆ Recombinant Protein | ||
ACHE-106R | Recombinant Rat ACHE Protein, His (Fc)-Avi-tagged | +Inquiry |
ACHE-04H | Active Recombinant Human ACHE Protein, His-tagged | +Inquiry |
ACHE-2415H | Recombinant Human ACHE Protein, His (Fc)-Avi-tagged | +Inquiry |
ACHE-36R | Recombinant Rhesus Macaque ACHE Protein, His (Fc)-Avi-tagged | +Inquiry |
Ache-511M | Recombinant Mouse Ache Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
ACHE-8345H | Native Human ACHE | +Inquiry |
◆ Lysates | ||
ACHE-2163MCL | Recombinant Mouse ACHE cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0032 | Acetylcholinesterase Assay Kit | +Inquiry |
Kit-0031 | Acetylcholinesterase Activity Colorimetric Assay Kit | +Inquiry |
Kit-0033 | Acetylcholinesterase Green Fluorescence Assay Kit | +Inquiry |
Kit-0034 | Acetylcholinesterase Red Fluorescence Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (8)
Ask a questionThe time required for different proteins varies, you can pay attention to the information on the product details page, or contact our experts directly.
Sure. We can customize proteins according to customer needs, including different tags, expression system, protein length, etc.
Because we can customize proteins of different lengths according to customer needs, please contact us if you are interested in this product.
Patients with Alzheimer disease often receive treatment with acetylcholinesterase inhibitors that mitigate symptoms by hindering ACh turnover.
Acetylcholinesterase is known to be distributed in nervous tissue such as the brainstem, cerebellum, and peripheral and autonomic nervous systems. Skeletal muscle also contains AChE with distribution patterns seemingly related to the type of muscle (fast versus slow twitch) and their specific function. AChE is also present on red blood cell membranes.
Although the primary function of AChE is to terminate neural transmission, investigators have found that AChE also plays a role in neural development. During fetal development, AChE contributes to morphogenesis in addition to its main enzymatic function.
Acetylcholinesterase exists as a monomer that often polymerizes into a dimer with a disulfide bond. Along with Van der Waals forces, two dimers may be linked to become tetramers.
The primary role of AChE is to terminate neuronal transmission and signaling between synapses to prevent ACh dispersal and activation of nearby receptors. They are an important component of pesticides and nerve agents.
Customer Reviews (2)
Write a reviewI have already recommended creative biomart products to many colleagues.
Received the product very quickly after placing the order, I am very satisfied.
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