Recombinant Rat ADAMTSL4 Protein
Cat.No. : | ADAMTSL4-508R |
Product Overview : | Recombinant Rat ADAMTSL4 full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Rat |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Adamtsl4 ADAMTS-like 4 [ Rattus norvegicus ] |
Official Symbol : | ADAMTSL4 |
Gene ID : | 310670 |
mRNA Refseq : | NM_001034012.1 |
Protein Refseq : | NP_001029184.1 |
MIM : | |
UniProt ID : | Q4FZU4 |
Products Types
◆ Recombinant Protein | ||
ADAMTSL4-328M | Recombinant Mouse ADAMTSL4 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAMTSL4-164R | Recombinant Rat ADAMTSL4 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAMTSL4-1327M | Recombinant Mouse ADAMTSL4 Protein | +Inquiry |
ADAMTSL4-33H | Recombinant Human ADAMTSL4 protein, GST-tagged | +Inquiry |
ADAMTSL4-32H | Recombinant Human ADAMTSL4 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ADAMTSL4-27HCL | Recombinant Human ADAMTSL4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (15)
Ask a questionADAMTSL4 protein interacts with various extracellular matrix components, including fibrillin-1, collagen, and elastin. It has also been shown to interact with growth factors and receptors, such as TGF-β receptors.
As of now, there are no clinical trials testing the use of ADAMTSL4 protein as a therapy. However, preclinical studies are ongoing to determine its potential for use as a therapeutic target in various conditions.
While ADAMTSL4 protein is not directly involved in Marfan syndrome, it has been shown to interact with fibrillin-1, a protein that is mutated in Marfan syndrome. Therefore, targeting ADAMTSL4 protein could potentially help to restore normal extracellular matrix function and prevent or slow down disease progression in Marfan syndrome.
While ADAMTSL4 has been shown to play a role in tissue repair, there is no evidence to suggest that it could be used to directly improve wound healing. However, further research may identify potential therapeutic targets.
At present, there are no drugs that specifically target ADAMTSL4 protein. However, drugs that target other components of the extracellular matrix may indirectly affect ADAMTSL4 function.
ADAMTSL4 protein is produced in various tissues throughout the body, including the retina, skin, and connective tissues. Its production is regulated by various factors, including growth factors and extracellular matrix components.
Mutations in the ADAMTSL4 gene have been associated with various disorders, including ectopia lentis (dislocated lens), isolated familial horizontal strabismus (eye misalignment), and various connective tissue disorders. The precise effects of these mutations on ADAMTSL4 protein function are not yet fully understood.
There is limited evidence to suggest that ADAMTSL4 protein may be involved in the development of connective tissue disorders such as Ehlers-Danlos syndrome and Loeys-Dietz syndrome. However, further research is needed to determine its precise role and potential therapeutic applications.
ADAMTSL4 protein could potentially be used to treat various connective tissue disorders, as well as craniofacial abnormalities and other conditions that involve abnormal extracellular matrix function.
Yes, ADAMTSL4 protein is being studied for its potential role in retinal diseases such as age-related macular degeneration (AMD) and retinal detachment. It has been shown to interact with various components of the extracellular matrix in the retina, and may play a role in maintaining retinal integrity.
ADAMTSL4 protein is being studied as a potential therapeutic target for Marfan syndrome, as it has been shown to interact with fibrillin-1, a protein that is affected in Marfan syndrome. However, further research is needed to determine its clinical applications.
Currently, ADAMTSL4 protein is not used as a therapy for any condition. However, it has shown potential as a therapeutic target in various conditions, including retinal diseases, craniofacial abnormalities, and Marfan syndrome, and research is ongoing to determine its potential clinical applications.
ADAMTSL4 protein has been shown to play a role in embryonic development, and may contribute to the development of craniofacial abnormalities. However, its potential therapeutic applications in this context are not yet clear.
ADAMTSL4 protein has been studied for its potential therapeutic applications in conditions such as retinal diseases, craniofacial abnormalities, Marfan syndrome, and various connective tissue disorders.
ADAMTSL4 protein is involved in the formation and maintenance of the extracellular matrix in the retina, and mutations in the ADAMTSL4 gene have been associated with various retinal disorders, including early-onset macular degeneration and retinal detachment. Therefore, ADAMTSL4 protein could potentially be used in the treatment of these conditions by restoring normal extracellular matrix function and preventing or slowing down disease progression.
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