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Recombinant Rat ADRA2B Protein

Cat.No. : ADRA2B-542R
Product Overview : Recombinant Rat ADRA2B full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rat
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Adra2b adrenoceptor alpha 2B [ Rattus norvegicus ]
Official Symbol : ADRA2B
Gene ID : 24174
mRNA Refseq : NM_138505.2
Protein Refseq : NP_612514.2
MIM :
UniProt ID : P19328

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (16)

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What are the potential implications of dysregulation of ADRA2B? 01/25/2023

Dysregulation of ADRA2B has been associated with various diseases and conditions, including hypertension, heart failure, diabetes, and asthma. Animal studies suggest that disruption of ADRA2B signaling can also contribute to neurological disorders such as depression and anxiety.

What kind of therapies can help regulate ADRA2B function? 01/07/2023

There are several different therapies that can help regulate ADRA2B function, including medication, psychotherapy, lifestyle changes, and natural remedies. Depending on the specific condition being treated, a combination of these therapies may be recommended.

What are the potential therapeutic applications of ADRA2B-targeted treatments? 04/28/2022

ADRA2B-targeted treatments have potential applications in the treatment of hypertension, heart failure, diabetes, and other diseases and conditions involving dysregulation of blood pressure, heart rate, and insulin secretion. However, more research is needed to fully understand the therapeutic potential and limitations of targeting the receptor in each of these contexts.

How can lifestyle changes and natural remedies help regulate ADRA2B function? 04/25/2022

Lifestyle changes, such as regular exercise, stress reduction techniques, and a healthy diet, can help regulate ADRA2B function by reducing stress and promoting overall physical and mental health. Natural remedies, such as herbal supplements, may also be beneficial, especially those containing compounds that target ADRA2B receptors, such as green tea extract or ashwagandha.

Are there any genetic variations that affect ADRA2B expression or activity? 06/21/2021

Yes, genetic variations in the ADRA2B gene have been identified that affect receptor expression or activity, and have been associated with various diseases such as hypertension, diabetes, and obesity.

Are there any FDA-approved drugs that target ADRA2B? 03/12/2021

Currently, there are no FDA-approved drugs that specifically target the ADRA2B receptor. However, there are drugs that target other adrenergic receptors, such as beta-adrenergic blockers that target the beta-adrenergic receptors, which can indirectly affect ADRA2B signaling.

Are there any natural compounds that target ADRA2B? 03/12/2021

Yes, there are natural compounds that have been shown to target ADRA2B receptors, such as epigallocatechin-3-gallate (EGCG), a polyphenol found in green tea. Other natural compounds, such as resveratrol and curcumin, have been shown to indirectly affect ADRA2B signaling. However, more research is needed to determine the efficacy of these natural compounds for treating diseases associated with ADRA2B dysregulation.

Are there any side effects associated with ADRA2B-targeted treatments? 06/03/2020

Like any medication or treatment, ADRA2B-targeted treatments can have side effects. Some of the potential side effects associated with these treatments include changes in heart rate and blood pressure, sleep disturbances, gastrointestinal issues, and changes in mood or behavior. The specific side effects will vary depending on the type of treatment and the individual patient.

Can ADRA2B-targeted treatments be used to treat psychological disorders? 08/08/2019

While ADRA2B-targeted treatments are still in development, there is evidence to suggest that they may be effective in treating psychological disorders. For example, some studies have found that medications that indirectly affect ADRA2B signaling, such as norepinephrine reuptake inhibitors, can improve symptoms of depression and anxiety. However, more research is needed to determine the safety and efficacy of ADRA2B-targeted treatments for psychological disorders.

How do ADRA2B agonists and antagonists differ in their mechanism of action? 02/11/2019

ADRA2B agonists bind to and activate the receptor, leading to a decrease in blood pressure and heart rate, as well as increased insulin secretion. ADRA2B antagonists, on the other hand, block the receptor, resulting in increased blood pressure and heart rate, and decreased insulin secretion.

How can knowledge about ADRA2B proteins be used in personalized medicine? 08/15/2018

Knowledge about ADRA2B proteins and their genetic variations can potentially be used in personalized medicine to identify patients who may benefit from ADRA2B-targeted treatments or who may be at increased risk for diseases associated with dysregulation of ADRA2B signaling. Personalized medicine may also involve tailoring drug doses and treatment regimens based on an individual's ADRA2B genotype and other factors, such as age and sex.

What are some challenges in developing ADRA2B-targeted treatments? 10/16/2017

Developing ADRA2B-targeted treatments can be challenging due to the complex role of the receptor in various physiological processes. Targeting ADRA2B specifically may also lead to off-target effects on other adrenergic receptors, which can cause unwanted side effects. Additionally, genetic variations in the ADRA2B gene can affect receptor activity in different ways, making it difficult to predict how ADRA2B-targeted treatments will affect individual patients.

How do ADRA2B proteins affect the cardiovascular system? 10/07/2017

ADRA2B proteins play a role in regulating the activity of the sympathetic nervous system, which controls many physiological functions, including heart rate and blood pressure. Activation of ADRA2B receptors can lead to decreased heart rate and blood pressure, while inhibition can lead to increased heart rate and blood pressure.

How are ADRA2B proteins studied in the medical field? 08/06/2017

ADRA2B proteins are studied in the medical field through various methods, including genetic studies, animal models, and clinical trials. Genetic studies involve identifying genetic variations in the ADRA2B gene that may contribute to disease risk or severity. Animal models are used to explore the physiological effects of disrupting or manipulating ADRA2B signaling in vivo. Clinical trials aim to evaluate the safety and efficacy of ADRA2B-targeted treatments in humans.

Can ADRA2B-targeted treatments be used to treat cardiovascular diseases? 11/01/2016

ADRA2B-targeted treatments have the potential to be used to treat cardiovascular diseases, such as hypertension and heart failure. However, more research is needed to determine the safety and efficacy of these treatments and to identify potential side effects.

Can meditation and mindfulness practices help regulate ADRA2B function? 01/22/2016

Yes, meditation and mindfulness practices have been shown to help regulate ADRA2B function by reducing stress and anxiety. Mindfulness practices specifically can help individuals become more aware of their thoughts and emotions, which can improve their ability to regulate their own stress response. However, more research is needed to fully understand the effects of these practices on ADRA2B function.

Customer Reviews (4)

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Reviews
07/12/2022

    This protein is of exceptional quality and purity, making it an ideal choice for my experimental needs.

    11/18/2018

      Its reliability ensures accurate and reproducible results, giving me confidence in my research.

      10/12/2018

        The exceptional technical support offered by the manufacturer is invaluable, allowing me to troubleshoot any issues I encounter and ensuring an optimal experimental outcome.

        02/26/2016

          I am grateful for the outstanding product and customer service provided by this company.

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