Recombinant Rat Ahr protein, His-tagged
Cat.No. : | Ahr-6846R |
Product Overview : | Recombinant Rat Ahr aa. (Val311~Thr579 (Accession # P41738)) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Rat |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 32.1kDa. |
Protein length : | Val311~Thr579 (Accession # P41738) |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 5.6. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in 20mM Tris, 500mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | Ahr aryl hydrocarbon receptor [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Ahr |
Synonyms : | ah receptor; aryl hydrocarbon receptor |
Gene ID : | 25690 |
mRNA Refseq : | NM_001308254.1 |
Protein Refseq : | NP_001295183.1 |
UniProt ID : | P41738 |
Products Types
◆ Recombinant Protein | ||
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Ahr-145M | Recombinant Mouse Ahr protein, His/GST-tagged | +Inquiry |
AHR-1443M | Recombinant Mouse AHR Protein | +Inquiry |
Ahr-3645M | Recombinant Mouse Ahr, His-tagged | +Inquiry |
◆ Lysates | ||
AHR-8962HCL | Recombinant Human AHR 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionThe expression and function of AHR can be influenced by genetic polymorphisms, DNA methylation patterns, and histone modifications, which may have implications in individual susceptibility to environmental toxins.
AHR is expressed in skin cells and plays a role in the response to environmental toxins, UV radiation, and the regulation of skin barrier function.
AHR is essential for normal embryonic development and organogenesis. It participates in the patterning and differentiation of various organs, including the heart and vasculature.
Yes, AHR activation can interfere with hormonal signaling pathways, leading to cross-talk with estrogen receptor signaling, and affecting hormonal homeostasis.
AHR can impact cell cycle progression and apoptosis by modulating the expression of genes involved in these processes, which can have implications in cancer biology.
AHR is involved in the regulation of immune responses and inflammation by affecting the differentiation and function of immune cells, such as T cells and dendritic cells.
AHR activation induces the expression of cytochrome P450 enzymes, particularly CYP1A1 and CYP1B1, which metabolize and detoxify various environmental pollutants and xenobiotics.
AHR forms a complex with co-activators or co-repressors upon ligand binding, leading to the modulation of gene expression. Downstream targets include cytochrome P450 enzymes (CYP1A1, CYP1B1), phase II detoxification enzymes, and cytokines.
AHR activation occurs upon binding to specific ligands, including polycyclic aromatic hydrocarbons (PAHs), halogenated aromatic hydrocarbons (HAHs), and tryptophan derivatives, such as indole-3-carbinol. Endogenous ligands are derived from cellular metabolism and the diet.
AHR activity can be regulated through various post-translational modifications, including phosphorylation and ubiquitination. Protein-protein interactions with chaperones and co-regulators also influence AHR function.
Customer Reviews (5)
Write a reviewThumbs up for this lab protein – it's top-notch!
I'm loving this lab protein – it's a research game-changer.
Five stars for this incredible lab protein – highly recommend.
The lab protein's performance has exceeded our expectations, and its versatility has enabled diverse applications within our research scope.
We've seen remarkable results with this lab protein.
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