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Recombinant Rat B2M protein(Met1-Met119), His-tagged

Cat.No. : B2M-1111R
Product Overview : Recombinant Rat B2M (P07151) (Met 1-Met 119) was expressed in HEK293, fused with a polyhistidine tag at the C-terminus.
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  • Gene Information
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Source : HEK293
Species : Rat
Tag : C-His
Protein length : Met1-Met119
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The secreted recombinant rat B2M comprises 110 amino acids and predicts a molecular mass of 13 kDa. The apparent molecular mass of the rat B2M is approximately 15 kDa in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 97 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : B2m beta-2 microglobulin [ Rattus norvegicus ]
Official Symbol : B2M
Synonyms : B2M; beta-2 microglobulin; beta-2-microglobulin;
Gene ID : 24223
mRNA Refseq : NM_012512
Protein Refseq : NP_036644

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the normal reference range for B2M? 11/19/2019

The normal reference range for B2M varies depending on age, gender, weight, individual differences, and other factors. In general, the normal reference range is between 0~3.0mg/L.

Why is B2M reduced? 11/16/2019

Causes of reduced B2M include liver and kidney failure, tuberculosis, HIV infection, rheumatoid arthritis, systemic lupus erythematosus and other diseases.

In which diseases does B2M play a role in the diagnosis and treatment? 09/20/2019

B2M plays an important role in the diagnosis and prognosis assessment of malignancies such as lymphoma and multiple myeloma. Elevated B2M levels can also indicate worsening or recurrence of certain autoimmune diseases, such as systemic lupus erythematosus.

What are the physiological functions of B2M? 07/29/2019

It has a variety of physiological functions in the immune system, including inducing immune response, participating in lymphocyte proliferation and differentiation, regulating immune tolerance, and participating in tumor immune surveillance.

What are the causes of elevated B2M? 06/05/2019

The levels can be affected by a variety of factors, such as cancer, inflammation, autoimmune diseases, infections, medications, etc.

How is B2M related to disease? 04/30/2019

This is associated with many diseases, including lymphoma, normal stress hydrocephalus, HIV infection, rheumatoid arthritis, nephrotic syndrome, cirrhosis, systemic lupus erythematosus, etc.

Customer Reviews (3)

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Reviews
10/08/2022

    To meet the needs of biological activity experiments

    01/25/2022

      High purity, no impurities.

      09/10/2020

        The expression level is high, which can meet the daily experimental needs.

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