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Recombinant Rat CADM3 Protein, His-tagged

Cat.No. : CADM3-1091R
Product Overview : Recombinant rat CADM3 (Q1WIM3) extracellular domain (Met 1-His 328) was expressed, fused with a polyhistidine tag at the C-terminus.
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  • Gene Information
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Source : HEK293
Species : Rat
Tag : His
Predicted N Terminal : Asn 23
Form : Lyophilized from sterile PBS, pH 7.51, 5%~8% trehalose and mannitol.
Molecular Mass : The recombinant rat CADM3 comprises 317 amino acids and predicts a molecular mass of 35 kDa. The apparent molecular mass of the ratCADM3 is approximately 35-40 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >90 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : Cadm3 cell adhesion molecule 3 [ Rattus norvegicus ]
Official Symbol : CADM3
Synonyms : CADM3; cell adhesion molecule 3; nectin-like protein 1; immunoglobulin superfamily member 4B; immunoglobulin superfamily, member 4B; Igsf4b; Necl-1;
Gene ID : 360882
mRNA Refseq : NM_001047103
Protein Refseq : NP_001040568
MIM :
UniProt ID :
Pathway : Adherens junctions interactions, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communicatio
Function : protein homodimerization activity; protein homodimerization activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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What are the implications of CADM3 mutations or dysregulation in neurological diseases like autism or schizophrenia? 07/29/2022

Mutations or dysregulation of CADM3 have been linked to neurological disorders like autism spectrum disorders and schizophrenia, highlighting its significance in neural function.

Can you explain the structure of CADM3 and its interactions with other proteins or ligands in neural adhesion processes? 09/20/2021

CADM3 has extracellular domains responsible for adhesion. It interacts with other synaptic proteins like neurexins and neuroligins, contributing to synaptic adhesion and signaling.

How does CADM3 contribute to synaptic adhesion and plasticity, and why is this important for neurological research? 06/12/2020

CADM3 mediates synaptic adhesion and facilitates synaptic plasticity, which is essential for learning and memory processes. Understanding CADM3's role is critical for advancing our knowledge of neurological disorders and cognitive function.

What is the primary function of CADM3 in cellular processes, and where is it typically expressed in the body? 02/03/2019

CADM3, also known as SynCAM3, is a cell adhesion molecule that plays a crucial role in synapse formation and neural connectivity. It is primarily expressed in neural tissues, particularly in neurons.

How does CADM3 expression change during brain development, and what roles does it play in neural differentiation and circuit formation? 11/09/2018

CADM3 expression varies during brain development and contributes to neural differentiation and circuit formation, aiding in proper brain function.

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08/04/2022

    The product's quality is exceptional.

    03/21/2020

      I couldn't be happier with the results I've seen.

      01/27/2018

        it's helped me achieve my fitness goals faster than I expected.

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