Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Rat Fbn1 protein, His-tagged

Cat.No. : Fbn1-2629R
Product Overview : Recombinant Rat Fbn1 aa. (Ile1475~Tyr1638 (Accession # Q9WUH8)) fused with N-terminal His tag was produced in E. coli cells.
  • Specification
  • Gene Information
  • Related Products
Description : Modulates early organogenesis and vascularization of the rat kidney.
Source : E. coli
Species : Rat
Tag : His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 19.0kDa
Protein length : Ile1475~Tyr1638 (Accession # Q9WUH8)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 4.9.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4
Gene Name : Fbn1 fibrillin 1 [ Rattus norvegicus (Norway rat) ]
Official Symbol : Fbn1
Synonyms : Fbn1; fibrillin 1; fibrillin-1
Gene ID : 83727
mRNA Refseq : NM_031825.1
Protein Refseq : NP_114013.1
UniProt ID : Q9WUH8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (7)

Ask a question
What potential therapeutic applications arise from targeting FBN1 in connective tissue disorders? 06/23/2023

Targeting FBN1 offers potential for treating connective tissue disorders by restoring matrix integrity and function.

How do genetic variations in FBN1 affect connective tissue disorders? 06/08/2023

Genetic mutations in FBN1 can lead to various connective tissue disorders, affecting tissue strength and flexibility.

What is the impact of altered FBN1 activity on cardiovascular health? 02/08/2022

Altered FBN1 activity is associated with cardiovascular conditions due to its role in maintaining blood vessel structure.

What role does FBN1 play in connective tissue development? 02/18/2021

FBN1 plays a critical role in the development of connective tissues, including tendons, ligaments, and blood vessels.

What is the primary role of FBN1 in extracellular matrix formation? 12/29/2019

FBN1, or Fibrillin-1, is essential for the formation of the extracellular matrix, providing structural support to tissues.

How does FBN1 interact with other extracellular matrix proteins? 10/02/2018

FBN1 interacts with other extracellular matrix proteins, such as elastin, in building and maintaining tissue architecture.

How does FBN1 contribute to tissue elasticity and structural integrity? 05/04/2017

It contributes to tissue elasticity and integrity by forming microfibrils that reinforce the matrix.

Customer Reviews (3)

Write a review
Reviews
10/12/2022

    Excellent in cell culture functionality

    05/03/2020

      Exceptional specificity in immunohistochemistry

      04/14/2020

        Highly stable and reliable in assays

        Ask a Question for All Fbn1 Products

        Required fields are marked with *

        My Review for All Fbn1 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends