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Recombinant Rat Fcgr3a protein, His & GST-tagged

Cat.No. : Fcgr3a-6759R
Product Overview : Recombinant Rat Fcgr3a aa. (Leu5~His241 (Accession # Q6XPU4)) fused with N-terminal His & GST tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Source : E. coli
Species : Rat
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 58.3kDa.
Protein length : Leu5~His241 (Accession # Q6XPU4)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.9.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Fcgr3a Fc fragment of IgG receptor IIIa [ Rattus norvegicus (Norway rat) ]
Official Symbol : Fcgr3a
Synonyms : Fcgr4; Fc fragment of IgG intermediate affinity IV receptor; Fc fragment of IgG, low affinity IIIa, receptor for (CD16); transmembrane receptor FcgammaRIII-X; Fc fragment of IgG receptor IIIa; Fc fragment of IgG, low affinity IIIa, receptor
Gene ID : 304966
mRNA Refseq : NM_207603.1
Protein Refseq : NP_997486.1
UniProt ID : Q6XPU4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does FCGR3A mediate immune cell activation and phagocytosis in response to antibody-opsonized targets? 07/29/2022

FCGR3A activates immune cells and mediates phagocytosis, aiding in the clearance of pathogens and antibody-coated targets.

What role does FCGR3A play in antibody-dependent cellular cytotoxicity, particularly in cancer immunotherapy? 03/03/2020

FCGR3A is key in antibody-dependent cellular cytotoxicity, crucial for the effectiveness of certain cancer immunotherapies.

How does genetic variation in the FCGR3A gene affect individual responses to monoclonal antibody treatments? 12/29/2018

Genetic variations in FCGR3A influence responses to monoclonal antibody treatments, affecting treatment efficacy.

What are the mechanisms by which FCGR3A regulates the balance between immune activation and tolerance? 12/06/2018

FCGR3A helps regulate the immune system's balance between activation and tolerance, preventing overactive immune responses.

How do alterations in FCGR3A expression or function affect the efficacy of vaccines? 08/12/2018

Changes in FCGR3A function or expression can influence vaccine efficacy, impacting immune system responses to vaccination.

How does FCGR3A contribute to the inflammatory response in infectious diseases? 01/25/2018

FCGR3A plays a role in the inflammatory response to infections, contributing to pathogen clearance and immune regulation.

What is the impact of FCGR3A expression on the development and severity of autoimmune diseases? 01/08/2018

FCGR3A expression impacts the development and severity of autoimmune diseases by modulating immune responses.

Customer Reviews (3)

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Reviews
12/28/2021

    Outstanding protein-protein interaction studies, boosts our experiments.

    02/04/2021

      Swift protein quantification, improves data reliability.

      11/21/2019

        Expertise in peptide synthesis, accelerates our peptide-based projects.

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