Recombinant Rat Hif1a protein, His-tagged
Cat.No. : | Hif1a-7720R |
Product Overview : | Recombinant Rat Hif1a aa. (Ser641~Asn810 (Accession # O35800)) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Rat |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 20.2kDa |
Protein length : | Ser641~Asn810 (Accession # O35800) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 8.6. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | Hif1a hypoxia inducible factor 1 alpha subunit [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Hif1a |
Synonyms : | MOP1; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1-alpha |
Gene ID : | 29560 |
mRNA Refseq : | NM_024359.1 |
Protein Refseq : | NP_077335.1 |
UniProt ID : | O35800 |
Products Types
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HIF1A-3111H | Recombinant Human HIF1A Protein, His (Fc)-Avi-tagged | +Inquiry |
HIF1A-2240H | Recombinant Human HIF1A Protein, His-tagged | +Inquiry |
HIF1A-2496R | Recombinant Rat HIF1A Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
HIF1A-787HCL | Recombinant Human HIF1A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionHIF1A shifts cellular metabolism from oxidative phosphorylation to glycolysis, conserving oxygen but producing less energy.
HIF1A modulates immune cell function, influencing responses like inflammation and immune cell migration in hypoxic tissues.
HIF1A upregulates the expression of angiogenic factors, promoting blood vessel formation to improve oxygen supply.
In cancer, HIF1A promotes tumor growth, survival, and metastasis under low oxygen conditions.
HIF1A activates the transcription of genes involved in oxygen delivery and metabolic adaptation to hypoxia.
Under normoxic conditions, HIF1A is rapidly degraded, but under hypoxia, it stabilizes, translocates to the nucleus, and activates target genes.
Therapeutic strategies targeting HIF1A aim to inhibit its activity in cancer or enhance it in conditions like ischemic heart disease.
Customer Reviews (3)
Write a reviewReliable product, satisfied customer.
Good value for money.
Product exceeded expectations.
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