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Recombinant Rat Il11ra1 protein, His & T7-tagged

Cat.No. : Il11ra1-1330R
Product Overview : Recombinant Rat Il11ra1 aa. (Thr24~Ala371 (Accession# Q99MF4) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Description : Receptor for IL-11; functions with signaling molecule gp130.
Source : E. coli
Species : Rat
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 41.9kDa
Protein length : Thr24~Ala371 (Accession# Q99MF4)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.1.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex
Gene Name : Il11ra1 interleukin 11 receptor subunit alpha 1 [ Rattus norvegicus (Norway rat) ]
Official Symbol : Il11ra1
Synonyms : Il11ra1; interleukin 11 receptor subunit alpha 1; interleukin-11 receptor subunit alpha; IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; IL-11RA; interleukin 11 receptor, alpha chain 1; interleukin-11 receptor alpha chain
Gene ID : 245983
mRNA Refseq : NM_139116.1
Protein Refseq : NP_620816.1
UniProt ID : Q99MF4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What are the advanced imaging techniques used to visualize the dynamic conformational changes of IL11RA1 upon ligand binding? 07/04/2022

Advanced imaging techniques visualize IL11RA1 conformational changes upon ligand binding.

Can you elaborate on the utilization of animal models and transgenic approaches to study the tissue-specific functions of IL11RA1? 04/15/2022

Animal models and transgenics study IL11RA1's tissue-specific functions.

How do reporter gene assays help in studying the transcriptional regulation of IL11RA1 gene expression? 02/28/2022

Reporter gene assays study IL11RA1 gene expression regulation.

Can you explain the role of high-throughput screening in identifying small molecules that modulate IL11RA1 activity? 10/02/2021

High-throughput screening identifies small molecules modulating IL11RA1 activity.

What insights have functional genomics studies provided regarding the role of IL11RA1 in disease pathogenesis? 09/22/2020

Functional genomics unveil IL11RA1's role in disease pathogenesis.

How does site-directed mutagenesis contribute to understanding the binding interface between IL11RA1 and IL11? 07/09/2020

Site-directed mutagenesis reveals the binding interface of IL11RA1 and IL11.

What methodologies like fluorescence resonance energy transfer (FRET) elucidate the intracellular signaling pathways activated by IL11RA1? 01/07/2020

Fluorescence resonance energy transfer (FRET) reveals IL11RA1 signaling pathways.

How are biophysical methods such as circular dichroism (CD) spectroscopy employed to investigate the secondary structure changes of IL11RA1? 01/26/2019

Circular dichroism (CD) spectroscopy probes IL11RA1 secondary structure changes.

How do proteomic analyses contribute to identifying IL11RA1-interacting proteins and potential signaling complexes? 09/18/2018

Proteomics identifies IL11RA1-interacting proteins and signaling complexes.

What strategies like surface plasmon resonance (SPR) aid in quantifying the binding kinetics between IL11RA1 and its downstream effectors? 01/02/2017

Surface plasmon resonance (SPR) quantifies IL11RA1 binding kinetics.

Customer Reviews (3)

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Reviews
08/14/2021

    Good for cytokine assays.

    02/01/2021

      Effective in signaling studies.

      01/09/2019

        Consistent bioactivity.

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