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Recombinant Rat Il6 protein, His-tagged

Cat.No. : Il6-481R
  • Specification
  • Gene Information
  • Related Products
Product overview : Recombinant Rat Il6 (P20607) aa. (Phe25~Thr211) fused with His tag was produced in HEK293F cells.
Description : A cytokine involved in development and possibly in neurodegenerative processes.
Source : HEK293F
Species : Rat
Tag : His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 23.3kDa; Accurate Molecular Mass: 23-33kDa as determined by SDS-PAGE reducing conditions.
Protein length : Phe25~Thr211
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 95%
Characteristic : Isoelectric point is 7.8.
Applications : SDS-PAGE; WB; ELISA; IP; CoIP; EMSA; Reporter Assays; Purification; Amine Reactive Labeling
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Concentration : 200ug/mL
Storage buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex
Gene Name : Il6 interleukin 6 [ Rattus norvegicus (Norway rat) ]
Official Symbol : Il6
Synonyms : Il6; interleukin 6; ILg6; Ifnb2; interleukin-6; IL-6; Interleukin 6 (interferon, beta 2)
Gene ID : 24498
mRNA Refseq : NM_012589.2
Protein Refseq : NP_036721.1
UniProt ID : P20607

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the dosage and usage of Il6? 07/15/2022

The dosage and usage of Il6 will vary according to the disease, and generally require individualized regulation by the physician according to the disease situation.

What are the pharmacokinetic properties of Il6? 06/16/2022

The pharmacokinetic characteristics of Il6 mainly include drug absorption, distribution, metabolism, excretion and other information.

Does Il6 have advantages in the treatment of multiple myeloma? 04/22/2022

Recombinant Il6 protein has a unique therapeutic advantage in the treatment of multiple myeloma. It can promote the proliferation and differentiation of hematopoietic stem cells and inhibit the growth of tumor cells.

Does Il6 have specific therapeutic effects for certain diseases? 05/27/2020

Il6 has specific therapeutic effects for certain diseases, such as rheumatoid arthritis, multiple myeloma and so on.

In which diseases is Il6 widely used? 11/20/2019

This protein is widely used in the treatment of rheumatoid arthritis, pneumonia, multiple myeloma, lymphoma, malignant tumors and other diseases.

What is the effect of Il6 on immune cells? 05/21/2019

The effects of Il6 on immune cells are mainly manifested as promoting cell proliferation and differentiation, regulating immune response, etc.

Customer Reviews (3)

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Reviews
03/05/2022

    Accurate localization and function within the cell.

    01/31/2021

      The binding affinity and affinity constant with the target are high.

      03/12/2020

        Can form a stable micellar structure.

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