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Recombinant Rat Muc5ac protein, His & T7-tagged

Cat.No. : Muc5ac-7628R
Product Overview : Recombinant Rat Muc5ac aa. (Val324~Gln406) fused with N-terminal His & T7 tag was produced in E. coli cells.
  • Specification
  • Gene Information
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Source : E. coli
Species : Rat
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 17.4kDa
Protein length : Val324~Gln406
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 5.4.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Muc5ac mucin 5AC, oligomeric mucus/gel-forming [ Rattus norvegicus (Norway rat) ]
Official Symbol : Muc5ac
Synonyms : mucin 5, subtypes A and C, tracheobronchial/gastric; LOW QUALITY PROTEIN: mucin-5AC; mucin 5, subtypes A and C
Gene ID : 682837
mRNA Refseq : XM_008760037.2
Protein Refseq : XP_008758259.1
UniProt ID : O35888

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How is MUC5AC produced and where is it mainly found in the body? 05/22/2022

MUC5AC is produced by goblet cells in the airway epithelium and is mainly found in mucus lining the respiratory tract.

In which respiratory conditions is MUC5AC expression often dysregulated or elevated? 06/25/2020

Dysregulated or elevated expression of MUC5AC is often observed in respiratory conditions such as asthma, chronic bronchitis, and cystic fibrosis.

What is the primary role of mucin 5AC (MUC5AC) in the respiratory system? 04/01/2019

Mucin 5AC (MUC5AC) primarily functions in the respiratory system by providing protection and lubrication to the airway epithelium.

What are the implications of abnormal MUC5AC expression in lung diseases? 01/16/2019

Abnormal MUC5AC expression in lung diseases can contribute to mucus hypersecretion, airway obstruction, and impaired respiratory function.

Are there specific signaling pathways or molecular mechanisms associated with the regulation of MUC5AC expression? 07/17/2018

Regulation of MUC5AC expression involves specific signaling pathways and molecular mechanisms, including the activation of transcription factors in response to inflammatory stimuli.

How does MUC5AC contribute to the defense against foreign particles and microorganisms in the respiratory tract? 06/27/2017

MUC5AC plays a crucial role in the defense against foreign particles and microorganisms by trapping and eliminating them from the respiratory tract.

What functions does MUC5AC serve in protecting and lubricating the epithelium of the airways? 07/24/2016

In protecting and lubricating the epithelium, MUC5AC helps prevent foreign particles and microorganisms from adhering to the airway surfaces.

Customer Reviews (3)

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Reviews
03/03/2022

    Positive feedback from other labs and researchers confirmed its standing as a valuable research tool.

    07/10/2018

      The product's innovative features hinted at its potential for advancing our research in uncharted territories.

      01/28/2018

        Compliance with industry standards minimized potential roadblocks in securing approvals for our experiments.

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