Recombinant Rat Npy protein, His & GST-tagged
Cat.No. : | Npy-7870R |
Product Overview : | Recombinant Rat Npy aa. (Pro31~Trp98) fused with N-terminal His & GST tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. Studies in the rat model of depression (Flinders Sensitive Line) show that this gene is downregulated in the hippocampus and the prefrontal cortex compared to the control ((Flinders Resistant Line). Alternatively spliced transcript variants of this gene have been described, but the function of all the variants is not known. |
Source : | E. coli |
Species : | Rat |
Tag : | His & GST |
Form : | Freeze-dried powder |
Molecular Mass : | 38kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Pro31~Trp98 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >92% |
Characteristic : | The isoelectric point is 6.4. |
Applications : | SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200μg/mL |
Storage buffer : | PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300 |
Reconstitution : | Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | Npy neuropeptide Y [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Npy |
Synonyms : | NPY02; RATNPY; RATNPY02; pro-neuropeptide Y |
Gene ID : | 24604 |
mRNA Refseq : | NM_012614.2 |
Protein Refseq : | NP_036746.1 |
UniProt ID : | P07808 |
Products Types
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◆ Lysates | ||
NPY-3726HCL | Recombinant Human NPY 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionWhile there are currently no NPY-based therapies approved for depression, research is exploring the potential of targeting NPY pathways for novel antidepressant treatments.
NPY has been shown to have anticonvulsant properties and may play a role in regulating seizure activity in the brain.
Research suggests that NPY-based therapies may have potential in the treatment of epilepsy, although more studies are needed.
NPY has been found to have an anxiolytic effect, meaning it can reduce anxiety and stress levels in the brain.
NPY has also been implicated in neurodegenerative disorders, such as Alzheimer's disease, and is being studied for its potential neuroprotective effects.
Customer Reviews (3)
Write a reviewThis aspect is crucial in maintaining the scientific rigor of my studies and strengthens the validity of my research findings.
the manufacturer's commitment to continuous improvement and innovation is evident in their constant efforts to enhance the NPY protein.
Its high purity and integrity ensure reliable and reproducible results, minimizing any potential variability in my experimental outcomes.
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