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Recombinant Rat Shbg Protein, His-tagged

Cat.No. : Shbg-587R
Product Overview : Recombinant Rat Shbg(Leu222~Ser358) fused with His tag at N-terminal was expressed in E. coli.
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  • Gene Information
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Description : Shbg played an important role in many functions.
Source : E. coli
Species : Rat
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 20.3kDa
Identity : Reconstitute in PBS or others
Protein length : Leu222~Ser358
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Gene Name : Shbg sex hormone binding globulin [ Rattus norvegicus ]
Official Symbol : Shbg
Synonyms : SHBG; sex hormone binding globulin; sex hormone-binding globulin; ABP; SBP; sex steroid-binding protein; testis-specific androgen-binding protein; Sex hormone binding globulin or androgen-binding protein (other gene product from ABP gene); Abpa;
Gene ID : 24775
mRNA Refseq : NM_012650
Protein Refseq : NP_036782
UniProt ID : P08689

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does SHBG interact with other proteins and receptors in the body? 12/07/2022

SHBG interacts with cell surface receptors, influencing cellular responses to sex hormones.

How is SHBG used as a diagnostic marker in clinical settings? 08/21/2022

SHBG levels are used to assess free testosterone levels, helping diagnose hormonal imbalances.

What factors can influence the levels of SHBG in the bloodstream? 04/16/2022

Factors influencing SHBG levels include age, sex, hormonal balance, and certain medical conditions.

What are the implications of abnormally high or low levels of SHBG? 03/19/2022

Abnormally high SHBG can reduce free testosterone, potentially leading to hypogonadism, while low SHBG can increase free testosterone, possibly contributing to conditions like polycystic ovary syndrome (PCOS) and insulin resistance.

In which organs or tissues is SHBG predominantly produced? 09/06/2021

SHBG is predominantly produced in the liver.

What is the primary biological role of Sex Hormone-Binding Globulin (SHBG) in the body? 01/23/2020

SHBG binds and transports sex hormones, particularly testosterone and estradiol, in the bloodstream.

How does SHBG regulate the bioavailability of sex hormones? 01/08/2020

By binding sex hormones, SHBG controls their free, bioavailable forms and regulates their activity.

Customer Reviews (3)

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Reviews
10/27/2022

    Very satisfied, worked perfectly.

    09/15/2021

      Fast shipping, product perfect.

      04/06/2021

        Excellent results in assay.

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