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Recombinant Rat TP53 Protein

Cat.No. : TP53-6230R
Product Overview : Recombinant Rat TP53 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rat
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : Tp53 tumor protein p53 [ Rattus norvegicus ]
Official Symbol : TP53
Gene ID : 24842
mRNA Refseq : NM_030989.3
Protein Refseq : NP_112251.2
MIM :
UniProt ID : P10361

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can TP53 status be used for cancer risk assessment and screening in individuals with a family history of cancer? 07/21/2022

Yes, identifying TP53 mutations in families with a history of early-onset cancers can help identify individuals at high risk for cancer and guide screening and prevention strategies.

What are the challenges in developing targeted therapies for TP53-mutated cancers? 05/21/2019

TP53 mutations are highly diverse, making it challenging to develop a one-size-fits-all therapy. Additionally, the p53 pathway is complex, and disrupting it can have unintended consequences.

Can TP53 status influence eligibility for certain clinical trials? 12/06/2018

Yes, TP53 mutation status can be a criterion for eligibility in specific clinical trials, especially those testing experimental treatments that may target the p53 pathway.

How might TP53 status affect decisions regarding surgery, chemotherapy, and radiation therapy? 08/13/2017

TP53 status can influence treatment decisions. For example, patients with TP53 mutations may require more aggressive treatment approaches or different chemotherapy regimens.

Are there targeted therapies specifically designed for TP53-mutated cancers? 06/05/2016

Currently, there are no specific targeted therapies approved solely for TP53-mutated cancers. However, research is ongoing to develop drugs that target the altered p53 pathway.

Customer Reviews (3)

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Reviews
02/26/2023

    By actively engaging with researchers and understanding their needs, manufacturers can contribute significantly to the success and impact of research involving the TP53 protein.

    11/05/2020

      This flexibility allows for tailored approaches and provides researchers with more options to study specific aspects of TP53 biology or its interactions with other molecules.

      07/24/2017

        Manufacturers can provide comprehensive product information, including data on the functionality, stability, and handling of TP53 protein.

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