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Recombinant Rhesus monkey ACO2 Protein, His-tagged

Cat.No. : ACO2-210R
Product Overview : Recombinant Rhesus monkey ACO2 full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Rhesus monkey
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : ACO2 aconitase 2, mitochondrial [ Macaca mulatta (Rhesus monkey) ]
Official Symbol : ACO2
Synonyms : ACO2; aconitate hydratase, mitochondrial;
Gene ID : 707441
mRNA Refseq : NM_001261164
Protein Refseq : NP_001248093
MIM :
UniProt ID : F7BKH7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What is the function of ACO2? 12/29/2022

ACO2 is involved in the TCA cycle, which is a critical process for energy production in cells. Specifically, it catalyzes the conversion of citrate to isocitrate, which is a crucial step in the cycle.

Can ACO2 mutations cause disease? 12/11/2022

Yes, mutations in the ACO2 gene have been associated with several disorders, including infantile cerebellar-retinal degeneration and mitochondrial encephalopathy. These conditions are characterized by a range of symptoms, including neurological and developmental abnormalities.

Can ACO2 be targeted for medical treatment?  10/05/2021

ACO2 is a potential target for cancer treatment, as it is overexpressed in several types of cancer cells. However, the development of drugs that target ACO2 is still in the early stages of research.

How does ACO2 differ from ACO1? 04/28/2021

ACO1 and ACO2 are two isoforms of aconitate hydratase, which catalyze the same reaction in the TCA cycle. However, ACO2 is primarily located in the mitochondria of cells, while ACO1 is located in the cytoplasm.

Is ACO2 involved in iron metabolism? 10/30/2018

Unlike ACO1, ACO2 is not involved in iron metabolism. Its role is primarily in energy production through the TCA cycle.

What happens if ACO2 is deficient? 09/26/2018

ACO2 deficiency has been associated with several disorders, including infantile cerebellar-retinal degeneration and mitochondrial encephalopathy. These conditions are characterized by various neurological and developmental abnormalities.

What is the structure of ACO2? 06/23/2018

ACO2 is a homodimeric enzyme composed of two identical subunits. Each subunit contains a catalytic domain and a regulatory domain, which work together to catalyze the isomerization of citrate to isocitrate.

How is ACO2 measured in the laboratory?  10/02/2017

ACO2 activity can be measured in the laboratory using a variety of techniques, including spectrophotometric assays and enzymatic activity assays. These assays typically involve measuring the rate of citrate isomerization to isocitrate in the presence of ACO2 and other necessary cofactors.

How is the activity of ACO2 regulated? 09/29/2017

ACO2 activity is regulated by a variety of factors, including substrate availability, pH, and post-translational modifications such as phosphorylation. Additionally, ACO2 activity can be modulated by other enzymes and metabolic pathways in the cell.

Does ACO2 have any other functions in addition to energy production? 06/30/2015

While ACO2 is primarily known for its role in energy production, recent research suggests that it may also play a role in other cellular processes. For example, studies have shown that ACO2 may be involved in regulating the immune response and cellular metabolism.

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