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Recombinant Rhesus Monkey CDH2 Protein, hIgG1-tagged

Cat.No. : CDH2-1741R
Product Overview : Recombinant Rhesus monkey CDH2 Protein (XP_014977198 ( aa.160-724)) was expressed in human HEK293 cells with hIgG1 tag.
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  • Gene Information
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Description : N-cadherin, also known as Cadherin-2 (CDH2) or neural cadherin (NCAD),a classical cadherin from the cadherin superfamily, composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. N-cadherin, as well as other cadherins, interact with N-cadherin on an adjacent cell in an anti-parallel conformation, thus creating a linear, adhesive "zipper". between cells. Cadherin-2 acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. In cardiac muscle, N-cadherin is an integral component in adherens junctions residing at intercalated discs, which function to mechanically and electrically couple adjacent cardiomyocytes.
Source : HEK293
Species : Rhesus monkey
Tag : hIgG1
Form : PBS, pH7.4.
Purity : > 95 %
Applications : ELISA; WB; Immunogen
Storage : -80 centigrade, Avoid freeze/thaw cycle.
Concentration : 1 mg/mL
Gene Name : CDH2 cadherin 2 [ Macaca mulatta (Rhesus monkey) ]
Official Symbol : CDH2
Synonyms : CDH2; cadherin 2; type 1; N-cadherin (neuronal); NCAD; cadherin-2; CD325; CDHN; N cadherin; N-cadherin 1; neural cadherin; neural-cadherin; cadherin 2; N-cadherin (neuronal); calcium-dependent adhesion protein; neuronal; CDw325;
Gene ID : 711526
mRNA Refseq : XM_015121712.1
Protein Refseq : XP_014977198

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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