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Recombinant Rhesus Monkey PI16 Protein, hIgG4-tagged

Cat.No. : PI16-1790R
Product Overview : Recombinant Rhesus monkey PI16 Protein (XP_014991646 ( aa.29-400)) was expressed in human HEK293 cells with hIgG4 tag.
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  • Gene Information
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Description : CD363 is a member of the cysteine-rich secretory protein (CRISP) family and is likewise known as CRISP9. PI-16 is a putative serine protease inhibitor and can serve as a binding protein for PSP94 (prostate secretory protein of 94 amino acids) termed PSPBP. Serum levels of PSP94 and PI-16 can reportedly serve as key targets for prostate cancer research. PI-16 is highly expressed by the activated/memory, FoxP3-bright subsets of regulatory T cells. PI-16-positive regulatory T cells expressed uniformly high levels of the chemokine receptors, CCR4 and CCR6, when compared with PI-16-negative T regulatory cells. The results suggest that the CCR4+CCR6+ regulatory T cells are capable of homing to inflammatory sites and regulating effector T cells such as CCR4+CCR6+ Th17-like cells. PI-16 is also expressed by subsets of memory CD4+ and CD8-bright T cells. It is not expressed by B cells or monocytes.
Source : HEK293
Species : Rhesus monkey
Tag : hIgG4
Form : PBS, pH7.4.
Purity : > 95 %
Applications : ELISA; WB; Immunogen
Storage : -80 centigrade, Avoid freeze/thaw cycle.
Concentration : 1 mg/mL
Gene Name : PI16 peptidase inhibitor 16 [ Macaca mulatta (Rhesus monkey) ]
Official Symbol : PI16
Synonyms : PI16; peptidase inhibitor 16; protease inhibitor 16; dJ90K10.5; MGC45378; microseminoprotein; beta binding protein; MSMBBP; PSP94-binding protein; cysteine-rich secretory protein 9; microseminoprotein; beta-binding protein; PSPBP; CRISP9; DKFZp586B1817;
Gene ID : 719301
mRNA Refseq : XM_015136160.1
Protein Refseq : XP_014991646

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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