Recombinant Rhesus Monkey VTCN1 Protein, hIgG1-tagged

• Cat.No.: VTCN1-1517R
• Product Overview: Recombinant Rhesus monkey VTCN1 Protein (XP_001103715 ( aa.25-259)) was expressed in human HEK293 cells with hIgG1 tag.

Specification

• Description: B7H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. B7H4 is highly expressed on a number of tumor cells, including breast cancer.
• Source: HEK293
• Species: Rhesus monkey
• Tag: hIgG1
• Form: PBS, pH7.4.
• Purity: > 95 %
• Applications: WB; ELISA; Immunogen
• Storage: -80 centigrade, Avoid freeze/thaw cycle.
• Concentration: 1 mg/mL

Gene Information

• Gene Name: VTCN1 V-set domain containing T-cell activation inhibitor 1 [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: VTCN1
• Synonyms: VTCN1; V-set domain containing T cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; B7 family member; H4; B7 superfamily member 1; B7 H4; B7H4; B7S1; B7X; FLJ22418; B7 family member; H4; T cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; immune costimulatory protein B7-H4; B7-H4; B7h.5; VCTN1; PRO1291; RP11-229A19.4
• Gene ID: 714123
• mRNA Refseq: XM_001103715.3
• Protein Refseq: XP_001103715