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sPLA2 Activity Assay Kit

Cat.No. : Kit-0699
Product Overview : PLA2 (sPLA2) Assay kit provides an accurate and convenient method for measurement of sPLA2 activity. This assay uses the 1,2-dithio analog of diheptanoyl phosphatidylcholine which serves as a substrate for most PLA2s (for example, bee and cobra venoms, pancreatic, etc.) with the exception of cytosolic PLA2. Upon hydrolysis of the thio ester bond at the sn-2 position by PLA2, free thiols are detected using DTNB (5,5-dithio-bis-(2-nitrobenzoic acid)).
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Storage : Stability: 1 year;Storage: -20°C;This kit will perform as specified if stored at -20°C and used before the expiration date indicated on the outside of the box.

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can PLA2 inhibitors help in reducing the risk of cardiovascular diseases? 04/03/2020

Yes, PLA2 inhibitors have been investigated for their potential in reducing cardiovascular risk, particularly in atherosclerosis.

How does PLA2 contribute to inflammation? 05/19/2019

PLA2 releases arachidonic acid, which serves as a precursor for pro-inflammatory eicosanoids, leading to inflammation.

How is PLA2 relevant in the context of neurodegenerative diseases? 08/24/2018

PLA2 dysfunction is implicated in neurodegenerative diseases like Alzheimer's and Parkinson's, making it a target for research and potential therapies.

Are there genetic variations in PLA2 associated with disease susceptibility? 09/15/2017

Genetic polymorphisms in PLA2 have been studied for their potential links to disease susceptibility, including inflammatory disorders.

Are there drugs that target PLA2 for therapeutic purposes? 02/20/2017

Yes, some drugs inhibit PLA2 activity to manage inflammation, as seen in the treatment of rheumatoid arthritis.

Customer Reviews (3)

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Reviews
01/24/2023

    A manufacturer that can deliver the protein promptly and reliably can save researchers time and allow them to proceed with their experiments without unnecessary delays.

    09/30/2019

      An PLA2 protein manufacturer that also offers related reagents such as antibodies or assay kits can streamline the research process.

      01/26/2019

        This support could range from assisting with experimental design to offering advice on optimal protein handling and storage conditions.

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