ACOT11

Official Full Name

acyl-CoA thioesterase 11

Background

This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.

Synonyms

ACOT11; acyl-CoA thioesterase 11; THEA, thioesterase, adipose associated; acyl-coenzyme A thioesterase 11; BFIT; BFIT1; KIAA0707; StAR related lipid transfer (START) domain containing 14; STARD14; THEM1; ACO11_HUMAN; ACOT 11; Acyl CoA thioester hydrolase 11; Acyl CoA thioesterase 11; Acyl coenzyme A thioesterase 11; Acyl-CoA thioester hydrolase 11; Adipose associated thioesterase; Adipose-associated thioesterase; BFIT 1; BFIT 2; BFIT2; Brown fat inducible thioesterase; Brown fat-inducible thioesterase; OTTHUMP00000046722; STARD 14; START domain containing 14; THEA; THEM 1; Thioesterase adipose associated; Thioesterase superfamily member 1; thioesterase, adipose associated; StAR-related lipid transfer (START) domain containing 14