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ACOT11A

Species Cat.# Product name Source (Host) Tag Protein Length Price
Zebrafish ACOT11A-5787Z Recombinant Zebrafish ACOT11A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ACOT11A involved in several pathways and played different roles in them. We selected most pathways ACOT11A participated on our site, such as Fatty Acyl-CoA Biosynthesis, Fatty acid, triacylglycerol, and ketone body metabolism, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACOT11A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Fatty Acyl-CoA BiosynthesisACOT13;THEM5;ACOT10;ACOT12;ACOT9.2;ACOT11B;ACOT11;ACSF2;ACOT2
Fatty acid, triacylglycerol, and ketone body metabolismTIAM2;G0S2;MED10;ACOT11;SLC25A1;CYP7A1;MED19;CPT1B;MED21
MetabolismMARCKSB;PIK3R6;SLC35B3;TMEM195;SLC35D2;PCBD1;NHLRC1;OAZ3;SLC6A8
Metabolism of lipids and lipoproteinsNFYAL;SACM1LB;FAM213B;NFYBA;G0S2;FABP12;MED9;MED16;ARSD
Triglyceride BiosynthesisACOT11A;ACOT12;ACOT9;ACSF2;ACOT9.1;ACOT7;ELOVL1A;DGAT1B;ACOT11B

ACOT11A has several biochemical functions, for example, lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACOT11A itself. We selected most functions ACOT11A had, and list some proteins which have the same functions with ACOT11A. You can find most of the proteins on our site.

Function Related Protein
lipid bindingSTARD13;CYP21A1;PFN3;PAQR5A;OSBPL11;CETP;HDLBP;BPIFA5;PSAP

ACOT11A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACOT11A here. Most of them are supplied by our site. Hope this information will be useful for your research of ACOT11A.

  • Q&As
  • Reviews

Q&As (13)

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Are there any challenges or limitations to the use of ACOT11A as a therapeutic target? 06/12/2020

One challenge to the use of ACOT11A as a therapeutic target is that it plays a complex and multifaceted role in lipid metabolism and energy balance, and its precise functions and mechanisms are not fully understood. Additionally, targeting a single protein such as ACOT11A is unlikely to provide a complete solution to complex metabolic disorders. More research is needed to identify the most effective and safe ways to modulate ACOT11A activity.

How does ACOT11A compare to other proteins involved in lipid metabolism as a therapeutic target? 03/19/2020

There are many other proteins involved in lipid metabolism that have been proposed as therapeutic targets for metabolic disorders. ACOT11A is one potential target among many, and its relative efficacy and safety as a therapeutic target compared to other proteins will depend on many factors such as its specificity, expression patterns, and functional properties.

Are there any drugs that target ACOT11A protein? 03/08/2020

There are currently no drugs available that specifically target ACOT11A protein, but some compounds have been identified that can modulate its activity or expression. For example, some studies have reported that natural compounds such as curcumin and resveratrol can upregulate ACOT11A expression and improve lipid metabolism in animal models of obesity and diabetes. Additionally, some synthetic compounds have been identified that can inhibit ACOT11A activity, which could have potential applications in the treatment of certain metabolic disorders.

Could ACOT11A be used as a biomarker for metabolic disorders? 12/24/2019

The expression and activity of ACOT11A have been shown to be altered in animal models and human studies of obesity, type 2 diabetes, and other metabolic disorders. However, more research is needed to determine whether ACOT11A could be used as a reliable biomarker for these conditions in clinical settings.

Could ACOT11A protein be used as a biomarker for metabolic disorders? 04/25/2019

While there is some evidence that altered ACOT11A expression or activity may be associated with certain metabolic disorders such as obesity, diabetes, and nonalcoholic fatty liver disease, more research is needed to determine whether it could be used as a reliable biomarker for these conditions. Some studies have suggested that measurement of ACOT11A activity or expression levels in blood or tissue samples could provide useful diagnostic or prognostic information for these diseases.

Could ACOT11A be used as a target for the development of new anti-obesity drugs? 11/26/2018

ACOT11A and other acyl-CoA thioesterases have been proposed as potential targets for the development of anti-obesity drugs, as they play a critical role in lipid metabolism and energy balance. However, more research is needed to identify specific compounds or agents that can modulate ACOT11A activity or expression levels in a safe and effective manner. Additionally, the complex and multifactorial nature of obesity and related metabolic disorders means that targeting a single protein such as ACOT11A is unlikely to provide a complete solution.

How might ACOT11A protein be targeted for therapeutic use? 06/11/2018

One potential therapeutic use of ACOT11A could involve the development of drugs or compounds that selectively upregulate its expression or activity to improve lipid metabolism and reduce the risk of metabolic disorders. Alternatively, inhibitors of ACOT11A could be developed to decrease fatty acid oxidation and improve metabolic function in conditions such as obesity and type 2 diabetes. The use of gene therapy to modulate ACOT11A expression levels could also be explored as a potential therapeutic approach.

Is ACOT11A protein expressed in all tissues of the body? 03/14/2018

ACOT11A expression levels vary between different tissues of the body and are highest in the liver, kidney, and adipose tissue, which are all involved in lipid metabolism. ACOT11A is also expressed in the brain, where it is thought to play a role in regulating fatty acid metabolism in neural cells.

Are there any genetic mutations or polymorphisms that affect ACOT11A activity? 10/07/2017

Some genetic variations in the ACOT11A gene have been identified that may affect protein expression or function, including single nucleotide polymorphisms (SNPs) and rare genetic mutations. However, the clinical significance of these variations and their effects on ACOT11A activity and lipid metabolism is not well understood and requires further research.

Are there any natural compounds or dietary factors that affect ACOT11A activity? 05/08/2017

Some natural compounds and dietary factors have been shown to affect ACOT11A activity and expression levels, including polyunsaturated fatty acids (PUFAs), resveratrol, and curcumin. PUFAs such as omega-3 fatty acids have been shown to upregulate ACOT11A expression and improve lipid metabolism in animal models and humans, while resveratrol and curcumin have been shown to upregulate ACOT11A expression and improve glucose and lipid metabolism in animal models of obesity and type 2 diabetes.

How is ACOT11A activity regulated in the body? 04/09/2017

ACOT11A activity is regulated by a variety of factors, including substrate availability, binding and interaction with other proteins, post-translational modifications, and changes in gene expression. For example, some studies have shown that ACOT11A activity is regulated by its interaction with the protein perilipin, which can modulate its ability to hydrolyze stored fatty acids.

Are there any side effects or risks associated with changing ACOT11A activity levels? 04/12/2016

More research is needed to fully understand the potential risks and side effects of targeting ACOT11A for therapeutic use. However, some studies have suggested that altering ACOT11A activity could have systemic effects on lipid metabolism and energy balance, which could have both positive and negative consequences for overall health. Additionally, the long-term safety and efficacy of using gene therapy or other approaches to modulate ACOT11A expression levels will need to be carefully evaluated.

What research has been done on the development of ACOT11A-targeted therapies? 02/18/2015

Some studies have explored the use of natural compounds such as polyunsaturated fatty acids and resveratrol to modulate ACOT11A activity and improve metabolic function. Other studies have investigated the development of synthetic compounds that could specifically target ACOT11A or related proteins. However, more research is needed before ACOT11A-targeted therapies can be developed and tested in humans.

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