Agtrl1
- Assay Kits
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Kit-1095 | Overall Exosome Capture and Quantification Assay Kit (Human Serum, Luminometric) | N/A | ||||
Kit-0909 | TR-FRET CAR Coactivator Assay Kit, goat | N/A | ||||
Kit-2190 | AGTRL1 Activated GPCR Internalization Assay Kit | N/A | ||||
Kit-2189 | AGTRL1 CHO-K1 β-Arrestin GPCR Assay Kit | N/A | ||||
Kit-1118 | Caspase-4 Colorimetric Assay Kit | N/A | ||||
Kit-2191 | cAMP AGTRL1 CHO-K1 GPCR Assay Kit | N/A | ||||
Kit-1119 | Caspase-2 Colorimetric Assay Kit | N/A | ||||
Kit-1120 | Ascorbic Acid Colorimetric Assay Kit II (FRASC) | N/A |
Agtrl1 involved in several pathways and played different roles in them. We selected most pathways Agtrl1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Agtrl1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Agtrl1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by Agtrl1 itself. We selected most functions Agtrl1 had, and list some proteins which have the same functions with Agtrl1. You can find most of the proteins on our site.
Function | Related Protein |
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Agtrl1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Agtrl1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Agtrl1.
- Q&As
- Reviews
Q&As (10)
Ask a questionAGTRL1, like other GPCRs, possesses a seven-transmembrane helical bundle domain, which accommodates its ligand-binding pocket and interacts with angiotensin II. Additionally, specific amino acid residues in the receptor's binding site determine its selectivity for angiotensin II and related ligands.
AGTRL1 activation influences the secretion of aldosterone, a hormone that regulates sodium and water balance in the kidneys.
Yes, AGTRL1 knockout animal models, such as mice lacking the AGTRL1 gene, have been valuable tools for studying the protein's functions in various physiological processes.
AGTRL1 is widely expressed in various tissues, including the cardiovascular system, brain, kidney, and adrenal glands.
AGTRL1 activates various intracellular signaling pathways, including the phospholipase C (PLC)-inositol trisphosphate (IP3) pathway and mitogen-activated protein kinase (MAPK) pathway.
Yes, AGTRL1 has been implicated in various other physiological processes, such as cell proliferation, cell migration, and angiogenesis.
Some studies have suggested that certain natural compounds, such as flavonoids and polyphenols, might affect AGTRL1 activity, but further investigation is necessary.
AGTRL1's activation by angiotensin II leads to vasoconstriction and increased blood pressure, contributing to hypertension.
There is emerging evidence suggesting that AGTRL1 may be involved in cancer development and progression, particularly in angiogenesis and tumor growth.
AGTRL1 interacts with angiotensin-converting enzyme (ACE) and angiotensin II type 1 receptor (AT1R) to modulate blood pressure. ACE converts angiotensin I to angiotensin II, which subsequently binds to AGTRL1 and AT1R, leading to vasoconstriction and increased aldosterone secretion.
Customer Reviews (5)
Write a reviewWow, this protein is incredible! It has really improved my experiments.
My colleagues and I are thrilled with the results we achieved using this protein.
The protein worked like magic in my lab. Highly recommended!
The ordering process was smooth, and the recombinant proteins arrived on time and intact
Quick delivery and secure packaging ensured my recombinant proteins arrived in perfect condition.
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