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Agtrl1

  • Assay Kits
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Agtrl1 involved in several pathways and played different roles in them. We selected most pathways Agtrl1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Agtrl1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

Agtrl1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by Agtrl1 itself. We selected most functions Agtrl1 had, and list some proteins which have the same functions with Agtrl1. You can find most of the proteins on our site.

Function Related Protein

Agtrl1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Agtrl1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Agtrl1.

  • Q&As
  • Reviews

Q&As (10)

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What are the structural features of AGTRL1 that contribute to its unique ligand binding and activation mechanism? 03/09/2022

AGTRL1, like other GPCRs, possesses a seven-transmembrane helical bundle domain, which accommodates its ligand-binding pocket and interacts with angiotensin II. Additionally, specific amino acid residues in the receptor's binding site determine its selectivity for angiotensin II and related ligands.

How is AGTRL1 involved in the regulation of sodium and water balance? 01/21/2022

AGTRL1 activation influences the secretion of aldosterone, a hormone that regulates sodium and water balance in the kidneys.

Are there any AGTRL1 knockout animal models used in research? 09/02/2021

Yes, AGTRL1 knockout animal models, such as mice lacking the AGTRL1 gene, have been valuable tools for studying the protein's functions in various physiological processes.

What is the tissue distribution of AGTRL1 in the human body? 05/12/2021

AGTRL1 is widely expressed in various tissues, including the cardiovascular system, brain, kidney, and adrenal glands.

What are the downstream signaling pathways activated by AGTRL1? 02/18/2021

AGTRL1 activates various intracellular signaling pathways, including the phospholipase C (PLC)-inositol trisphosphate (IP3) pathway and mitogen-activated protein kinase (MAPK) pathway.

Does AGTRL1 have any non-blood-pressure-related functions? 07/07/2020

Yes, AGTRL1 has been implicated in various other physiological processes, such as cell proliferation, cell migration, and angiogenesis.

Are there any natural compounds known to modulate AGTRL1 activity? 12/03/2019

Some studies have suggested that certain natural compounds, such as flavonoids and polyphenols, might affect AGTRL1 activity, but further investigation is necessary.

How does AGTRL1 contribute to hypertension? 11/29/2019

AGTRL1's activation by angiotensin II leads to vasoconstriction and increased blood pressure, contributing to hypertension.

Can AGTRL1 play a role in cancer progression? 09/14/2018

There is emerging evidence suggesting that AGTRL1 may be involved in cancer development and progression, particularly in angiogenesis and tumor growth.

How does AGTRL1 interact with other components of the renin-angiotensin system to regulate blood pressure and fluid balance? 06/26/2018

AGTRL1 interacts with angiotensin-converting enzyme (ACE) and angiotensin II type 1 receptor (AT1R) to modulate blood pressure. ACE converts angiotensin I to angiotensin II, which subsequently binds to AGTRL1 and AT1R, leading to vasoconstriction and increased aldosterone secretion.

Customer Reviews (5)

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Reviews
08/12/2021

    Wow, this protein is incredible! It has really improved my experiments.

    01/26/2021

      My colleagues and I are thrilled with the results we achieved using this protein.

      06/21/2020

        The protein worked like magic in my lab. Highly recommended!

        10/03/2019

          The ordering process was smooth, and the recombinant proteins arrived on time and intact

          11/09/2018

            Quick delivery and secure packaging ensured my recombinant proteins arrived in perfect condition.

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