aldob
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  • Official Full Name
  • aldolase B, fructose-bisphosphate
  • Background
  • Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related housekeeping genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
  • Synonyms
  • ALDOB; aldolase B, fructose-bisphosphate; fructose-bisphosphate aldolase B; ALDB; ALDO B; ALDOB_HUMAN; Aldolase 2; Aldolase B; Aldolase B fructose bisphosphate; Aldolase2; AldolaseB; EC 4.1.2.13; Fructose bisphosphate aldolase B; Liver type aldolase; Liver-type aldolase; OTTHUMP00000021803; OTTHUMP00000021804; aldolase B, fructose-bisphosphatase; ALDO2
Cat.#:ALDOB-1918HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Aldolase B, Fructose-Bisphosphate, His-tagged
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Cat.#:ALDOB-456HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ALDOB Protein, GST-tagged
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Cat.#:ALDOB-505HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ALDOB Protein, GST-tagged
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Cat.#:ALDOB-9567HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ALDOB, His-tagged
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Cat.#:ALDOB-1817CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ALDOB
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Cat.#:ALDOB-9718ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ALDOB
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Cat.#:ALDOB-8911HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ALDOB 293 Cell Lysate
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