api5
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  • Official Full Name
  • apoptosis inhibitor 5
  • Background
  • This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
  • Synonyms
  • API5; apoptosis inhibitor 5; AAC 11; AAC11; API5 like 1; API5L1; fibroblast growth factor 2 interacting factor 2; migration inducing protein MIG8; FIF; antiapoptosis clone 11 protein; migration-inducing protein MIG8; cell migration-inducing gene 8 protein
Cat.#:API5-2310HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human API5 Protein, MYC/DDK-tagged
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Cat.#:API5-1171HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human API5 protein, His-tagged
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Cat.#:API5-681HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human API5 protein, GST-tagged
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Cat.#:API5-1770MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse API5 Protein
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Cat.#:Api5-3581MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Api5, His-tagged
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Cat.#:API5-356RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey API5 Protein, His-tagged
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Cat.#:API5-1613CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken API5
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Cat.#:API5-9945ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish API5
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API5 Related Articles

Accialini, P; Hernandez, SF; et al. A link between Notch and progesterone maintains the functionality of the rat corpus luteum. REPRODUCTION 149:1-10(2015).
Xiao, ZG; Sperl, B; et al. Metformin and salinomycin as the best combination for the eradication of NSCLC monolayer cells and their alveospheres (cancer stem cells) irrespective of EGFR, KRAS, EML4/ALK and LKB1 status. ONCOTARGET 5:12877-12890(2014).