This gene is a member of the apolipoprotein L gene family, and it is present in a cluster with other family members on chromosome 6. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids, including cholesterol, and/or allow the binding of lipids to organelles. In addition, expression of this gene is up-regulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta. Alternative splicing results in multiple transcript variants.
APOL3; apolipoprotein L, 3; apolipoprotein L3; APOLIII; CG12 1; ApoL III; Apolipoprotein L 3; Apolipoprotein L III; Apolipoprotein LIII; TNF inducible protein CG12 1; CG12_1; apoL-III; apolipoprotein L-III; TNF-inducible protein CG12-1; CG121