ABCA2
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Official Full Name
ATP-binding cassette, sub-family A (ABC1), member 2
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Overview
ATP-binding cassette sub-family A member 2 is a protein that in humans is encoded by the ABCA2 gene. -
Synonyms
ABCA2; ATP-binding cassette, sub-family A (ABC1), member 2; ATP-binding cassette sub-family A member 2; OTTMUSP00000013051; ATP-binding cassette 2; ATP-binding cassette transporter 2; Abc2; AI413825; mKIAA1062; D2H0S1474E;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- E.Coli or Yeast
- HEK293
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | ABCA2-13H | Recombinant Human ABCA2 protein, His-tagged | E.coli | His | ||
Human | ABCA2-032H | Recombinant Human ABCA2 Protein, GST-tagged | Wheat Germ | GST | ||
Mouse | Abca2-12M | Recombinant Mouse Abca2 protein, His-tagged | E.coli | His | ||
Mouse | Abca2-3729M | Recombinant Mouse Abca2, His-tagged | E.Coli or Yeast | His | 2434 | |
Rat | ABCA2-393R | Recombinant Rat ABCA2 Protein | Mammalian Cell | His | ||
Rat | ABCA2-48R | Recombinant Rat ABCA2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | ABCA2-48R-B | Recombinant Rat ABCA2 Protein Pre-coupled Magnetic Beads | HEK293 |
- Involved Pathway
- Protein Function
- Interacting Protein
ABCA2 involved in several pathways and played different roles in them. We selected most pathways ABCA2 participated on our site, such as ABC transporters, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ABC transporters | ABCB3L1;ABCD2;ABCB7;Abcb1b;ABCB5;ABCA4;TAP1;ABCD4;ABCD3A |
Lysosome | SLC11A2;NAGLU;ACP5;ATP6V0A1;ATP6V0B;Abca2;PPT2;NPC2;ACP5A |
ABCA2 has several biochemical functions, for example, ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCA2 itself. We selected most functions ABCA2 had, and list some proteins which have the same functions with ABCA2. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | ITPK1A;CARKD;AXL;CAMKK1A;ENTPD1;ADCK2;DNAJA3B;SYK;IRAK1 |
ATPase activity | HAND2;TOR1A;PSMD6;KIF7;ABCG4B;SWSAP1;KIF15;KIF20A;ERCC3 |
ATPase activity, coupled to transmembrane movement of substances | ABCA4;ABCG3;ABCB8;ABCD1;ABCG2D;ABCB10;ABCC12;IPO8;SFRP5 |
nucleotide binding | ARL15A;SBK3;RPS6KAL;ATP1A1A.2;DDX19;SFRS3A;TUBA8L2;HSPA12A;KIF5AA |
transporter activity | FABP2;SLC37A4;AP1G1;TTPAL;SLC12A3;LCN12;CPNE7;RBP2B;ATP5O |
ABCA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCA2.
- Q&As
- Reviews
Q&As (10)
Ask a questionABCA2 is most highly expressed in the fetal and adult brain, spinal cord, ovaries and leukocytes.
It may be a lipid transporter that modulates cholesterol sequestration in late endosomes/lysosomes. ABCA2 regulates the production of amyloid-beta by modulating the activation of signaling pathways that regulate the transcription of amyloid precursor proteins by regulating sphingolipid metabolism or by its role in the γ-secretase processing of APP. And it may play a role in myelin formation.
Sure, Creative BioMart supports custom protein production services.
To improve the solubility and facilitate the subsequent experimental operation, our ABCA2 protein products use GST or His tags for your choice.
We offer a variety of expression systems, including E. coli, Yeast, Wheat Germ, and Mammalian Cell expression systems.
Creative BioMart offers recombinant ABCA2 proteins of several species, including human, mouse, and rat.
We will ensure the safety of the products on the road by putting them in ice bags or additional packaging outside the package according to the characteristics of the products.
Discounts are available for first-time purchases and for holidays. For specific promotions, please contact our customer service staff. Thank you for your inquiry and we look forward to your order.
ABCA2 is enriched in brain tissue and may play a role in neural development.
ATP binding cassette subfamily A member 2, and this protein is a member of the superfamily of ATP-binding cassette (ABC) transporters.
Customer Reviews (3)
Write a reviewI purchased the Abca2 recombinant protein and the quality is excellent, saving me weeks of research time.
Customer service representatives have provided valuable assistance in helping to decide which products best meet our research needs.
Creative BioMart's customer service is excellent, friendly and efficient, making it a worthwhile long-term partner.
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