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ADIPOQ

  • Official Full Name

    adiponectin, C1Q and collagen domain containing

  • Overview

    Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
  • Synonyms

    ADIPOQ; adiponectin, C1Q and collagen domain containing; APN; Acdc; apM1; 30kDa; GBP28; adipo; Acrp30; adiponectin; adipocyte-specific protein AdipoQ; adipocyte complement related protein; 30 kDa adipocyte complement-related protein; adipocyte complement-related 30 kDa protein; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Cattle
  • Chicken
  • Dog
  • Human
  • Mouse
  • Pig
  • Porcine
  • Rabbit
  • Rat
  • Rhesus Macaque
  • CHO
  • E. coli
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293F
  • HEK293T
  • Human
  • Human Cell
  • Human cells
  • Human Serum
  • Insect cell
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Porcine
  • Wheat Germ
  • Yeast
  • C
  • His
  • DDK
  • Fc
  • Flag
  • GST
  • hFc
  • HIS
  • His (Fc)
  • Avi
  • His|GST
  • His|S
  • His|T7
  • SUMO
  • human|IgG1|Fc
  • MYC
  • Myc|DDK
  • N/A
  • N
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ADIPOQ-4957H Active Recombinant Human Adiponectin, C1Q And Collagen Domain Containing Human N/A
Human ADIPOQ-7300H Active Recombinant Human ADIPOQ protein, His-tagged HEK293 His Glu 19 - Asn 244
Human ADIPOQ-4956H Active Recombinant Human Adiponectin, C1Q And Collagen Domain Containing Human N/A
Human ADIPOQ-490H Active Recombinant Human Adiponectin, C1Q And Collagen Domain Containing HEK293 N/A
Human ADIPOQ-47H Active Recombinant Human ADIPOQ, Trimeric Form HEK293 N/A
Human ADIPOQ-254H Active Recombinant Human ADIPOQ protein, His-tagged Insect Cell His
Human ADIPOQ-255H Active Recombinant Human ADIPOQ protein E.coli N/A
Human ADIPOQ-169H Recombinant Human Adiponectin, C1Q And Collagen Domain Containing Mammalian cells N/A
Human ADIPOQ-7301H Recombinant Human ADIPOQ protein, Fc-tagged HEK293 human/IgG1/Fc Glu19-Asn244
Human ADIPOQ-693H Recombinant Human ADIPOQ, 145aa E.coli N/A
Human ADIPOQ-256H Recombinant Human ADIPOQ protein, DDK-tagged CHO DDK Gln18-Asn244
Human ADIPOQ-3647H Recombinant Human ADIPOQ, His-tagged E.coli His
Human ADIPOQ-45H Recombinant Human ADIPOQ, Flag-tagged HEK293 N/A
Human ADIPOQ-1098H Recombinant Human ADIPOQ protein, hFc-tagged HEK293 hFc Met1-Asn244
Human ADIPOQ-392H Recombinant Human ADIPOQ Protein, GST-tagged Wheat Germ GST
Human ADIPOQ-14H Recombinant Human ADIPOQ Protein, His/S-tagged E.coli His/S
Human ADIPOQ-199H Recombinant Human ADIPOQ, His-tagged Insect Cell His
Human ADIPOQ-133H Recombinant Human ADIPOQ protein, His-tagged Insect Cell His
Human ACRP30-3197H Recombinant Human ACRP30 Insect Cell N/A 244
Human ADIPOQ-251H Recombinant Human ADIPOQ protein, DDK-tagged Insect Cell DDK
Human ADIPOQ-1849H Recombinant Human Adiponectin, C1Q And Collagen Domain Containing E.coli N/A
Human ADIPOQ-253H Recombinant Human ADIPOQ protein, His-tagged HEK293 His Glu19-Asn244
Human ADIPOQ-19H Recombinant Human ACRP30 headless, FLAG-tagged HEK293 Flag
Human ADIPOQ-391H Recombinant Human ADIPOQ Protein E.coli N/A
Human ADIPOQ-856H Recombinant Human ADIPOQ protein, Flag-tagged HEK293 Flag
Human ADIPOQ-211H Recombinant Human ADIPOQ HEK293 N/A
Human ADIPOQ-252H Recombinant Human ADIPOQ protein, DDK-tagged Insect Cell DDK et-Gln18-Asn244
Human ADIPOQ-42H Recombinant Human ADIPOQ, Globular Domain, His-tagged E.coli His
Human ADIPOQ-209H Recombinant Human ADIPOQ, His-tagged E.coli His
Human ADIPOQ-210H Recombinant Human ADIPOQ, His-tagged E.coli HIS
Human ADIPOQ-1526HCL Recombinant Human ADIPOQ cell lysate Human Cell N/A
Human ADIPOQ-1061H Recombinant Human Adiponectin Protein Human cells His
Human ADIPOQ-1376H Recombinant Human ADIPOQ Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ADIPOQ-4360H Recombinant Human ADIPOQ Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ADIPOQ-01H Active Recombinant Human ADIPOQ Protein E.coli
Human ADIPOQ-02H Recombinant Human ADIPOQ Protein, His-tagged Insect cell His 106-242
Human ADIPOQ-03H Recombinant Human ADIPOQ Protein E. coli 15-244
Human ADIPOQ-06H Active Recombinant Human ADIPOQ Protein E.coli 144 amino acids
Human ADIPOQ-196A Active Recombinant Human ADIPOQ Protein HEK293
Human ADIPOQ-610H Recombinant Human ADIPOQ protein, His-tagged E. coli His 1-244 aa
Human ADIPOQ-200H Recombinant Human ADIPOQ protein, His-tagged Insect Cells His Met1-Asn244
Human ADIPOQ-0396H Recombinant Human ADIPOQ Protein (Glu19-Asn244), N-His-tagged E.coli N-His Glu19-Asn244
Human ADIPOQ-444A Active Recombinant Human ADIPOQ Protein (227 aa) E.coli 227
Human ADIPOQ-0065H Recombinant Human ADIPOQ Protein HEK293 cells
Human ADIPOQ-0395H Recombinant Human ADIPOQ Protein, Tag Free E.coli Tag Free
Human ADIPOQ-215H Native Human Adiponectin Human Serum N/A 226AA
Human ADIPOQ-0394H Recombinant Human ADIPOQ Protein (Glu19-Asn244), C-His-tagged Mammalian cells C-His Glu19-Asn244
Human ADIPOQ-300A Active Recombinant Human ADIPOQ Protein CHO
Human ADIPOQ-087H Recombinant Human ADIPOQ Protein, Fc-tagged HEK293 Fc 244
Human ADIPOQ-4360H-B Recombinant Human ADIPOQ Protein Pre-coupled Magnetic Beads HEK293
Mouse Adipoq-79M Active Recombinant Mouse Adipoq, FLAG-tagged HEK293 Flag
Mouse Adipoq-5600M Active Recombinant Mouse Adiponectin, C1Q And Collagen Domain Containing, His-tagged Mammalian cells His
Mouse Adipoq-501M Active Recombinant Mouse Adipoq Protein, His-tagged Insect Cell His
Mouse Adipoq-48M Active adiponectin, C1Q and collagen domain containing HEK293 N/A
Mouse Adipoq-204M Recombinant Mouse Adipoq protein, His-tagged HEK293 His Met1-Asn247
Mouse Adipoq-75M Recombinant Mouse Adiponectin, Globular Domain E.coli N/A
Mouse Adipoq-500M Recombinant Mouse Adipoq Protein E.coli N/A
Mouse Adipoq-13M Recombinant Mouse Adiponectin Protein, His/S-tagged E.coli His/S
Mouse Adipoq-117M Recombinant Mouse Adipoq, Globular Domain, His-tagged E.coli His
Mouse Adipoq-46M Recombinant Mouse Adipoq HEK293 N/A
Mouse Adipoq-5373M Recombinant Mouse Adiponectin, C1Q And Collagen Domain Containing E.coli N/A
Mouse Adipoq-32M Recombinant Mouse Adipoq protein, Flag-tagged E.coli Flag
Mouse Adipoq-47M Recombinant Mouse Adiponectin, C1Q and Collagen Domain Containing, His-tagged E.coli His
Mouse Adipoq-33M Recombinant Mouse Adipoq protein, His-tagged E.coli His
Mouse Adipoq-216M Recombinant Mouse Adipoq HEK293 N/A
Mouse Adipoq-118M Recombinant Mouse Adipoq (Trimer), Flag-tagged HEK293 Flag
Mouse ADIPOQ-2209MCL Recombinant Mouse ADIPOQ cell lysate Human Cell N/A
Mouse Adipoq-032M Recombinant Mouse Adipoq Protein, His-tagged E.coli His
Mouse Adipoq-17M Active Recombinant Mouse Adipoq Protein E.coli
Mouse Adipoq-5596M Recombinant Mouse Adipoq Protein (Glu18-Asn247), C-His tagged Mammalian cells C-His Glu18-Asn247
Mouse Adipoq-035M Recombinant Mouse Adipoq Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Adipoq-033M Active Recombinant Mouse Adipoq Protein, His-tagged Insect Cell His
Mouse Adipoq-7153M Recombinant Mouse Adipoq Protein, His-tagged E.coli His 18-247
Mouse ADIPOQ-1362M Recombinant Mouse ADIPOQ Protein, His-tagged Insect Cell His
Mouse Adipoq-3985M Recombinant Mouse Adipoq Protein (Met1-Asn247), C-His tagged E.coli C-His Met1-Asn247
Mouse Adipoq-034M Active Recombinant Mouse Adipoq Protein E.coli
Mouse Adipoq-349M-B Recombinant Mouse Adipoq Protein Pre-coupled Magnetic Beads HEK293
Mouse Adipoq-81M Recombinant Mouse Adipoq Protein, His-tagged E.coli N-His Asp19-Asn247+LEHHHHHH
Mouse Adipoq-7149M Recombinant Mouse Adipoq Protein E.coli 111-247
Mouse Adipoq-443A Active Recombinant Mouse Adipoq Protein (227 aa) E.coli 227
Mouse Adipoq-7152M Active Recombinant Mouse Adipoq Protein HEK293
Mouse Adipoq-349M Recombinant Mouse Adipoq Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Adipoq-3986M Recombinant Mouse Adipoq Protein (Met1-Asn247), C-His tagged Mammalian cells C-His Met1-Asn247
Mouse Adipoq-5241M Recombinant Mouse Adipoq protein, His-tagged E.coli His 104-247aa
Rat Adipoq-502R Active Recombinant Rat Adipoq Protein E.coli N/A
Rat Adipoq-195R Recombinant Rat Adipoq, FLAG-tagged HEK293 Flag
Rat Adipoq-5443R Recombinant Rat Adiponectin, C1Q And Collagen Domain Containing E.coli N/A
Rat Adipoq-194R Recombinant Rat Adipoq protein, His-tagged E.coli His
Rat Adipoq-82R Recombinant Rat Adipoq Protein, His&SUMO-tagged E.coli N-His&SUMO Ile19-Asn244
Rat Adipoq-80R Recombinant Rat Adipoq Protein, His-tagged HEK293F N-His Ile19-Asn244
Rabbit ADIPOQ-83R Recombinant Rabbit ADIPOQ Protein, His-tagged E.coli N-His Gln18-Asn244
Dog ADIPOQ-189D Recombinant Dog ADIPOQ, Globular Domain, FLAG-tagged HEK293 Flag
Dog ADIPOQ-2646D Recombinant Dog ADIPOQ Protein, His-GST-tagged E.coli His-GST Gln18~Asn244
Dog ADIPOQ-188D Recombinant Dog ADIPOQ, FLAG-tagged HEK293 Flag
Bovine ADIPOQ-5773B Recombinant Bovine ADIPOQ protein, His-tagged Yeast His 18-240aa
Bovine ADIPOQ-4473B Recombinant Bovine ADIPOQ protein, His-SUMO-tagged E.coli His-SUMO 18-240aa
Cattle ADIPOQ-2645C Recombinant Cattle ADIPOQ protein, His-tagged E.coli His Ala103~Glu240 (Accession # Q3Y5Z3)
Porcine ADIPOQ-267P Recombinant Porcine Adiponectin, C1Q And Collagen Domain Containing, FLAG-tagged Porcine Flag
Porcine ADIPOQ-218P Recombinant Porcine ADIPOQ, Flag-tagged HEK293 Flag
Rhesus Macaque ADIPOQ-247R Recombinant Rhesus monkey ADIPOQ Protein, His-tagged Mammalian Cell His
Rhesus Macaque ADIPOQ-75R-B Recombinant Rhesus Macaque ADIPOQ Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ADIPOQ-75R Recombinant Rhesus Macaque ADIPOQ Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Pig ADIPOQ-2648P Recombinant Pig ADIPOQ protein, His & GST-tagged E.coli His/GST Gly17~Glu243 (Accession # Q6PP07)
Pig ADIPOQ-79P Recombinant Pig ADIPOQ Protein, His-tagged CHO N-His Gln18-Glu243
Chicken ADIPOQ-2647C Recombinant Chicken ADIPOQ protein, His & T7-tagged E.coli His/T7 Met32~Arg244 (Accession # Q6QWE7)
Chicken ADIPOQ-7114C Recombinant Chicken ADIPOQ Mammalian Cell His
Chicken ADIPOQ-0010C Recombinant Chicken ADIPOQ Protein (Ser105-Arg244), C-His-tagged E.coli C-His Ser105-Arg244
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ADIPOQ Related Articles
  • ADIPOQ Related Research Area

ADIPOQ involved in several pathways and played different roles in them. We selected most pathways ADIPOQ participated on our site, such as PPAR signaling pathway, AMPK signaling pathway, Adipocytokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADIPOQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PPAR signaling pathwayPDPK1B;CYP4A10;MMP1;RXRA;ACOX2;GK2;Scd2;ACAA1A;RXRB
AMPK signaling pathwayCREB3L4;PPP2R1B;PIK3R5;PCK1;PRKAB1;G6PC;TBC1D1;PPP2R2B;RAB2A
Adipocytokine signaling pathwayACSL1B;RXRGA;LEP;TRAF2;ACSL1A;NFKBIAB;ACSBG1;LEPB;G6PC3
Type II diabetes mellitusPIK3R3;INSR;PKM;SOCS3;PIK3R2;INS2;SOCS1;PRKCZ;IKBKB
Non-alcoholic fatty liver disease (NAFLD)COX5A;NDUFB3;INS2;MAPK10;PIK3R1;NDUFB4;PRKAB2;NDUFB5;NDUFA2

ADIPOQ has several biochemical functions, for example, cytokine activity, hormone activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADIPOQ itself. We selected most functions ADIPOQ had, and list some proteins which have the same functions with ADIPOQ. You can find most of the proteins on our site.

Function Related Protein
cytokine activityFAM3D;GREM1;SLURP1;CMTM8;CMTM2;IL8L2;CD40LG;GDF15;IFNG
hormone activityPOMC;PRL7C1;ADIPOQ;CSHL1;INSL5B;RETN;PYYA;PRL7A2;STC1
identical protein bindingDYNLT1A;ACTN2;S100A4;STAC3;MNS1;CCT7;CNTN2;DHX8;DAPK3
protein bindingCATSPERG2;GZMB;FNBP1;APLP2;ITGB4;TUB;CXXC1;PLAC9;BRAT1
protein homodimerization activityUGT1A6;TIMM9;GNB2L1;TFAP4;RCHY1;TMEM173;STK10;EVLA;ECE1
receptor bindingLRRC4B;UTS2;EPB49;PECI;ANXA1;SERPINE1;TNFSF13B;CROT;EPHX2
sialic acid bindingFCN1;AGRN;SELE;SELP;ADIPOQ;L1CAM;ST8SIA3;Siglece;ST8SIA2

ADIPOQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADIPOQ here. Most of them are supplied by our site. Hope this information will be useful for your research of ADIPOQ.

C1QTNF9B; C1QTNF9

Cai, X; Gan, Y; et al. The adiponectin gene single-nucleotide polymorphism rs1501299 is associated with hepatocellular carcinoma risk. CLINICAL & TRANSLATIONAL ONCOLOGY 16:166-172(2014).
Pang, YF; Dong, J; et al. Characterization, Neurosteroid Binding and Brain Distribution of Human Membrane Progesterone Receptors delta and epsilon (mPR delta and mPR epsilon) and mPR delta Involvement in Neurosteroid Inhibition of Apoptosis. ENDOCRINOLOGY 154:283-295(2013).
  • Q&As
  • Reviews

Q&As (12)

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Can ADIPOQ proteins be used in cancer treatment? 06/24/2022

There is limited research on the use of ADIPOQ proteins in cancer treatment. However, some studies have suggested that ADIPOQ proteins may have a protective effect against certain types of cancers, including breast, colon, and prostate cancer.

Can ADIPOQ proteins be used in fertility treatments? 03/04/2022

Various conditions and diseases can affect ADIPOQ protein levels, including type 2 diabetes, obesity, metabolic syndrome, polycystic ovary syndrome, and certain cancers.

Can ADIPOQ levels be modulated through lifestyle changes? 01/14/2022

Yes, ADIPOQ levels can be modulated through lifestyle changes. Regular exercise and weight loss can increase ADIPOQ levels in the blood, while a diet high in saturated fats and sugar can decrease ADIPOQ levels.

Can ADIPOQ proteins have an impact on cardiovascular health? 07/14/2021

Yes, ADIPOQ proteins have been shown to have a protective effect on cardiovascular health. High levels of ADIPOQ proteins are associated with lower risk of cardiovascular disease, while low levels of ADIPOQ proteins are associated with increased risk.

How can lifestyle changes affect ADIPOQ protein levels? 02/05/2021

Lifestyle changes such as diet and exercise can significantly affect ADIPOQ protein levels. Eating a healthy diet and maintaining a healthy weight can increase circulating levels of ADIPOQ proteins, while sedentary lifestyle and obesity can decrease ADIPOQ protein levels.

How are ADIPOQ proteins related to obesity? 08/25/2019

Low levels of ADIPOQ proteins in the circulation have been associated with obesity and an increased risk of metabolic disorders such as insulin resistance and type 2 diabetes. High levels of ADIPOQ proteins, on the other hand, have been associated with better insulin sensitivity and a lower risk of metabolic disorders.

Are there any medications that can affect ADIPOQ levels? 07/30/2019

Some medications, such as thiazolidinediones (TZDs), commonly used to treat type 2 diabetes, can increase ADIPOQ levels and improve insulin sensitivity. However, other medications, such as glucocorticoids, used to treat inflammatory conditions, can reduce ADIPOQ levels and worsen insulin resistance.

How can ADIPOQ proteins be measured? 09/30/2018

ADIPOQ protein levels can be measured in the circulation using a blood test or through adipose tissue biopsies. The blood test is a more commonly used diagnostic tool to evaluate ADIPOQ protein levels due to its non-invasive nature.

What are some conditions and diseases that may affect ADIPOQ protein levels? 04/28/2017

Can ADIPOQ proteins be used as a biomarker for metabolic disorders? 09/27/2016

Yes, measuring circulating levels of ADIPOQ proteins can be used as a biomarker for metabolic disorders such as insulin resistance and type 2 diabetes. Low levels of ADIPOQ proteins are associated with an increased risk of these disorders.

Are there any medications that target ADIPOQ proteins? 08/03/2016

Currently, there are no medications that target ADIPOQ proteins directly. However, drugs that improve insulin sensitivity and metabolic function, such as thiazolidinediones (TZDs) and metformin, have been shown to increase circulating levels of ADIPOQ proteins.

What are some potential future applications of ADIPOQ proteins in medicine? 04/26/2016

As research continues to explore the role of ADIPOQ proteins in various physiological processes, they may have potential future applications for the prevention and treatment of metabolic disorders, cardiovascular disease, infertility, and certain types of cancer. Additionally, ADIPOQ proteins may serve as a biomarker for disease and treatment response.

Customer Reviews (5)

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Reviews
04/15/2019

    the quality of the ADIPOQ protein used in experiments is of utmost importance and can significantly impact the accuracy and reliability of the results obtained.

    05/12/2018

      The packaging and shipping of the protein were both efficient and effective, ensuring that the product arrived in good condition and ready to use.

      03/05/2018

        The protein's stability and shelf-life have exceeded my expectations, allowing me to use it for multiple experiments without worrying about degradation or loss of potency.

        09/04/2017

          In this regard, using a protein of very high quality that meets your experimental needs is essential.

          08/01/2016

            It will ensure that your results are both valid and reproducible, providing you with valuable insights into the expression and function of ADIPOQ.

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