Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

APOM

  • Official Full Name

    apolipoprotein M

  • Overview

    Apolipoproteins are plasma lipoproteins that function as transporters of lipids and cholesterol in the circulatory system. Chylomicrons are a fundamental class of apolipoproteins containing very low-density lipoproteins (VLDL), intermediate-density lipopr
  • Synonyms

    APOM; apolipoprotein M; G3a; NG20; protein G3a; NG20-like protein; alternative name: G3a, NG20; apo-M; HSPC336; MGC22400;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Dog
  • Horse
  • Human
  • Mouse
  • Pig
  • Rat
  • Zebrafish
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • His
  • Fc
  • Flag
  • GST
  • His (Fc)
  • Avi
  • Met|His
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human APOM-716H Active Recombinant Human APOM Protein, Met & His-tagged E.coli Met/His Cys23-Asn188
Human APOM-3654H Recombinant Human APOM, Flag-tagged HEK293 Flag
Human APOM-2054H Recombinant Human Apolipoprotein M, His-tagged E.coli His
Human APOM-541H Recombinant Human APOM Protein, His-tagged Yeast His
Human APOM-718H Recombinant Human APOM protein, GST-tagged Wheat Germ GST
Human APOM-26747TH Recombinant Human APOM, His-tagged E.coli His 23-188aa
Human APOM-540H Recombinant Human APOM Protein, Fc-tagged HEK293 Fc
Human APOM-1594HCL Recombinant Human APOM cell lysate Human Cell N/A
Human APOM-0344H Recombinant Human APOM Protein (Met1-Asn188), C-His-tagged Mammalian cells C-His Met1-Asn188
Human APOM-2471H Recombinant Human APOM Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human APOM-518H Recombinant Human APOM Protein, His-tagged E.coli His Ala8~Asn188
Human APOM-0343H Recombinant Human APOM Protein (Ala8-Asn188), His-tagged E.coli His Ala8-Asn188
Human APOM-3636H Recombinant Human APOM Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human APOM-1241HF Recombinant Full Length Human APOM Protein, GST-tagged In Vitro Cell Free System GST 188 amino acids
Human APOM-2543H Recombinant Human APOM protein, His-GST-tagged E.coli His/GST 1-188aa
Mouse APOM-1808M Recombinant Mouse APOM Protein Mammalian Cell His
Mouse Apom-519M Recombinant Mouse Apom Protein, His-tagged E.coli His Met20~Lys190
Mouse APOM-641M-B Recombinant Mouse APOM Protein Pre-coupled Magnetic Beads HEK293
Mouse Apom-1664M Recombinant Mouse Apom Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse APOM-2209M Recombinant Mouse APOM Protein (1-190 aa), His-tagged Yeast His 1-190 aa
Mouse APOM-641M Recombinant Mouse APOM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Apom-3577R Recombinant Rat Apom, His-tagged E.Coli or Yeast His 190
Rat APOM-729R Recombinant Rat APOM Protein Mammalian Cell His
Rat APOM-385R-B Recombinant Rat APOM Protein Pre-coupled Magnetic Beads HEK293
Rat APOM-385R Recombinant Rat APOM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Apom-521R Recombinant Rat Apom Protein, His-tagged E.coli His Met20~Lys190
Dog APOM-516D Recombinant Dog APOM Protein, His-tagged E.coli His Cys23~Asn188
Horse APOM-517H Recombinant Horse APOM Protein, His-tagged E.coli His Gln22~Asn188
Zebrafish APOM-7870Z Recombinant Zebrafish APOM Mammalian Cell His
Pig APOM-520P Recombinant Pig APOM Protein, His-tagged E.coli His Tyr21~Asn188
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • APOM Related Articles
  • APOM Related Research Area

APOM involved in several pathways and played different roles in them. We selected most pathways APOM participated on our site, such as Retinoid metabolism and transport, Signal Transduction, Visual phototransduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with APOM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Retinoid metabolism and transportRBP1;BCO2;APOA4B.2;RBP4;AKR1C6;APOA4A;BCO2A;BCO2L;LRP10
Signal TransductionCGNB;BCO2;AMOTL2A;CCBP2;SH2B3;LEO1;RIT1;WIF1;CRABP2A
Visual phototransductionDHRS9;METAP2A;ABCA4A;METAP1;RGS9BP;GRK7;CLPS;DHRS3A;GUCA1E

APOM has several biochemical functions, for example, antioxidant activity, lipid transporter activity, phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APOM itself. We selected most functions APOM had, and list some proteins which have the same functions with APOM. You can find most of the proteins on our site.

Function Related Protein
antioxidant activityMT3;CAT;TP53INP1;KDM3B;TRP53INP1;APOM;APOE;S100A9;APOA4
lipid transporter activityMTP;MTTP;APOA4;APOBB.1;VTG2;VTG6;VTG5;VTG1;GM2A
phospholipid bindingSDPR;PLA2G7;AGAP1;APOA5;PLA2G2A;FABP1;MYOF;SHC1;SPTBN2

APOM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOM here. Most of them are supplied by our site. Hope this information will be useful for your research of APOM.

C8orf30A; KLF6; d-mannose

Burkart, KM; Manichaikul, A; et al. APOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema. EUROPEAN RESPIRATORY JOURNAL 43:1003-1017(2014).
Huang, Y; Liu, Y; et al. Apolipoprotein m (APOM) levels and APOM rs805297 G/T polymorphism are associated with increased risk of rheumatoid arthritis. JOINT BONE SPINE 81:32-36(2014).
  • Q&As
  • Reviews

Q&As (12)

Ask a question
Can genetic variations in the APOM gene influence APOM protein levels? 02/24/2023

Yes, genetic variations in the APOM gene can impact APOM protein levels. Certain single nucleotide polymorphisms (SNPs) or mutations within the APOM gene have been associated with altered APOM expression levels. For example, specific APOM gene variants have been linked to lower APOM protein levels in plasma and changes in HDL cholesterol levels, which may contribute to cardiovascular disease risk.

Where is APOM protein primarily expressed? 11/11/2022

APOM protein is mainly expressed in the liver and kidneys. It is also present in other tissues, such as the intestines, adrenal glands, and spleen, but at lower levels.

Are there any known regulators of APOM protein expression? 08/27/2021

Yes, there are several known regulators of APOM protein expression. Transcription factors, such as hepatocyte nuclear factor 1 (HNF-1), liver X receptors (LXRs), and peroxisome proliferator-activated receptor gamma (PPARγ), have been identified as regulators of APOM gene expression. Additionally, factors like insulin, statins, and sex hormones (such as estrogen) can also influence APOM protein levels.

Are there any interactions between APOM protein and other proteins or molecules? 06/02/2021

Yes, APOM protein can interact with other proteins and molecules. In addition to binding to S1P, APOM has been shown to interact with components of the HDL particle, such as apolipoprotein A-I (apoA-I). It can also interact with enzymes involved in the metabolism of lipids, such as sphingosine kinase 1 (SphK1) and sphingosine-1-phosphate lyase (S1PL), which regulate S1P levels.

Can APOM protein be used as a biomarker for any diseases? 07/21/2020

APOM protein has been investigated as a potential biomarker for certain diseases. Research suggests that APOM levels in plasma or HDL particles could be used as a biomarker for evaluating cardiovascular risk and predicting the progression of metabolic disorders. However, further studies are needed to establish its utility as a clinical biomarker.

Does APOM protein have any known genetic variants or mutations? 05/26/2020

Yes, there are several known genetic variants and mutations in the APOM gene. Some studies have linked certain APOM gene variants to altered levels of APOM protein, which can impact lipid metabolism and the risk of developing cardiovascular diseases.

Are there any drug targets related to APOM protein? 10/12/2019

Given the role of APOM protein in lipid metabolism and its association with cardiovascular diseases, it has been considered as a potential drug target. However, no specific drugs targeting APOM are currently available. Further research is needed to explore potential therapeutic strategies aimed at modulating APOM levels or function for clinical applications.

Are there any known therapeutic strategies targeting APOM protein? 08/16/2019

Currently, there are no approved therapeutic strategies specifically targeting APOM protein. However, given its involvement in lipid metabolism and cardiovascular health, manipulating APOM levels or function could hold therapeutic potential. Future research may explore approaches such as gene therapy, potential drug candidates, or interventions aimed at modulating APOM expression or its interaction with S1P to potentially impact lipid disorders and cardiovascular diseases.

Is APOM protein associated with any diseases? 05/15/2018

APOM protein has been implicated in various diseases, particularly those related to lipid metabolism and cardiovascular health. For example, low levels of APOM in HDL particles have been associated with increased risk of atherosclerosis, coronary artery disease, and impaired glucose metabolism.

Can APOM protein affect the composition of HDL particles? 08/01/2017

Yes, APOM protein can influence the composition of HDL particles. Its binding to S1P within HDL can modify the lipid content and structure of these particles. This, in turn, can impact the functionality and biological properties of HDL, such as its ability to promote reverse cholesterol transport and exert anti-inflammatory effects.

How is APOM protein involved in the metabolism of sphingosine-1-phosphate? 07/30/2017

APOM protein binds to sphingosine-1-phosphate (S1P) and helps transport it within high-density lipoprotein (HDL) particles. This interaction with APOM stabilizes S1P and allows it to circulate in the bloodstream, playing a role in various biological processes, including immune cell trafficking, angiogenesis, and vascular biology.

What cellular processes are influenced by APOM protein? 07/11/2016

APOM protein is involved in several cellular processes, including lipid metabolism, lipoprotein biogenesis and remodeling, immune cell activation and migration, endothelial cell integrity, and vascular homeostasis. Its interaction with S1P and its role in HDL metabolism have implications for various physiological and pathological processes, such as atherosclerosis, inflammation, and cardiovascular health.

Customer Reviews (4)

Write a review
Reviews
04/08/2021

    Securing a protein of exceptional quality is crucial to meet the demands of my experiments, and I am confident that the APOM protein offered by the manufacturer will fulfill my requirements.

    09/18/2018

      This reliable and punctual supply enables me to proceed with my experiments without unnecessary delays, ensuring an efficient research process.

      05/18/2018

        the APOM protein, combined with the manufacturer's outstanding technical support and commitment to delivering high-quality products, presents an excellent opportunity for my research.

        07/11/2016

          Whether it's troubleshooting guidance, experimental design suggestions, or elucidating optimal storage conditions, their expertise can significantly accelerate the progress of my trials.

          Ask a Question for All APOM Products

          Required fields are marked with *

          My Review for All APOM Products

          Required fields are marked with *

          logo

          FOLLOW US

          Terms and Conditions        Privacy Policy

          Copyright © 2024 Creative BioMart. All Rights Reserved.

          Contact Us

          • /

          Stay Updated on the Latest Bioscience Trends