ARTN

The ARTN protein activates various signaling pathways, including the RET receptor tyrosine kinase pathway and the AKT and MAPK/ERK pathways, to mediate its neurotrophic effects.

Yes, the ARTN protein has neuroprotective effects and can promote the survival of neurons under conditions of stress or injury, such as oxidative stress or neuronal damage.

Dysregulation of the ARTN protein has been implicated in neurodegenerative diseases, including Parkinson's disease and Alzheimer's disease. Further research is needed to understand the underlying mechanisms.

Yes, the ARTN protein is involved in the development of the nervous system. It plays a role in guiding growing axons and promoting the survival and differentiation of neurons during development.

The potential therapeutic use of the ARTN protein is being explored, particularly for neurodegenerative diseases, but further research is needed to evaluate its effectiveness and safety.

Yes, the ARTN protein has immunomodulatory properties. It can influence immune cell activity and promote anti-inflammatory responses in certain contexts.

As of now, no specific mutations in the ARTN gene linked to neurological disorders have been reported. However, ongoing genomic studies might uncover any potential disease associations.

Yes, the ARTN protein has been implicated in pain perception. It has been shown to influence the sensitivity of sensory neurons and modulate pain signaling pathways.