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BCS1L

  • Official Full Name

    BCS1-like (S. cerevisiae)

  • Overview

    This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Two alternatively spliced transcripts encoding the same protein have been described.
  • Synonyms

    BCS1L; BCS1-like (S. cerevisiae); BCS1 (yeast homolog) like , BCS1 like (yeast); mitochondrial chaperone BCS1; BCS; Bjornstad syndrome; BJS; GRACILE syndrome; h BCS; Hs.6719; BCS 1; BCS 1L; BCS1 (yeast homolog) like; BCS1; BCS1 like; BCS1 like protein; Bjornstad syndrome (pili torti and deafness); FLNMS; GRACILE; H BCS1; Mitochondrial complex III assembly; PTD; h-BCS1; BCS1-like protein; OTTHUMP00000164147; OTTHUMP00000206492; OTTHUMP00000206493; OTTHUMP00000206494; OTTHUMP00000206495; OTTHUMP00000206496; OTTHUMP00000206497; h-BCS;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Chicken
  • Danio rerio (Zebrafish) (Brachydanio rerio)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rhesus Macaque
  • Xenopus laevis (African clawed frog)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BCS1L-179H Recombinant Human BCS1L Protein, GST-tagged Wheat Germ GST
Human BCS1L-178H Recombinant Human BCS1L Protein, GST-tagged Wheat Germ GST
Human BCS1L-26667TH Recombinant Human BCS1L, His-tagged E.coli His
Human BCS1L-167HCL Recombinant Human BCS1L cell lysate N/A
Human BCS1L-5566H Recombinant Human BCS1L Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human BCS1L-2464H Recombinant Human BCS1L Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BCS1L-1559HF Recombinant Full Length Human BCS1L Protein, GST-tagged In Vitro Cell Free System GST 419 amino acids
Mouse BCS1L-2364M Recombinant Mouse BCS1L Protein Mammalian Cell His
Mouse Bcs1l-1853M Recombinant Mouse Bcs1l Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse BCS1L-1006M-B Recombinant Mouse BCS1L Protein Pre-coupled Magnetic Beads HEK293
Mouse BCS1L-1006M Recombinant Mouse BCS1L Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL30213BF Recombinant Full Length Bovine Mitochondrial Chaperone Bcs1(Bcs1L) Protein, His-Tagged E.coli expression system His Full Length (1-419)
Danio rerio (Zebrafish) (Brachydanio rerio) RFL4781DF Recombinant Full Length Danio Rerio Mitochondrial Chaperone Bcs1(Bcs1L) Protein, His-Tagged E.coli expression system His Full Length (1-420)
Homo sapiens (Human) RFL28917HF Recombinant Full Length Human Mitochondrial Chaperone Bcs1(Bcs1L) Protein, His-Tagged E.coli expression system His Full Length (1-419)
Mus musculus (Mouse) RFL30069MF Recombinant Full Length Mouse Mitochondrial Chaperone Bcs1(Bcs1L) Protein, His-Tagged E.coli expression system His Full Length (1-418)
Rhesus Macaque BCS1L-528R Recombinant Rhesus monkey BCS1L Protein, His-tagged Mammalian Cell His
Rhesus Macaque BCS1L-356R-B Recombinant Rhesus Macaque BCS1L Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque BCS1L-356R Recombinant Rhesus Macaque BCS1L Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Xenopus laevis (African clawed frog) RFL30520XF Recombinant Full Length Xenopus Laevis Mitochondrial Chaperone Bcs1(Bcs1L) Protein, His-Tagged E.coli expression system His Full Length (1-419)
Zebrafish BCS1L-11399Z Recombinant Zebrafish BCS1L Mammalian Cell His
Chicken BCS1L-1658C Recombinant Chicken BCS1L Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

BCS1L involved in several pathways and played different roles in them. We selected most pathways BCS1L participated on our site, such as Metabolism of proteins, Mitochondrial protein import, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCS1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metabolism of proteinsPAPPA;TBCA;CTSH;PFDN4;NAPG;TMED10;EXOSC8;IGFBP6B;IGFBP2A
Mitochondrial protein importTIMM17B;PAM16;CHCHD4;SAMM50;COX17;DNAJC19;GRPEL2;HSCB;LDHD

BCS1L has several biochemical functions, for example, ATP binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BCS1L itself. We selected most functions BCS1L had, and list some proteins which have the same functions with BCS1L. You can find most of the proteins on our site.

Function Related Protein
ATP bindingPEBP1;UBE2D1B;CHST13;PLK4;PRKCBB;NLRP11;STK17A;ATP8A1;EIF2AK2
protein bindingMOV10;RHOG;ZNF26;ATP6V1C2;ULK1;ING4;CCDC24;BLK;DBNL

BCS1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCS1L here. Most of them are supplied by our site. Hope this information will be useful for your research of BCS1L.

LETM1; DNAJA1; DDX24; VPS26A; Myh9; Rbm8a

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