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BEX2

Official Full Name

brain expressed X-linked 2
Overview

This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms

BEX2; brain expressed X-linked 2; protein BEX2; DJ79P11.1; BEX 1; BEX 2; BEX1; Brain expressed X linked 2; Brain expressed X linked protein 2 homolog; brain expressed X-linked 1; HBEX2; HGR74-h; uncharacterized hypothalamus protein HBEX2; X-linked protein; OTTHUMP00000023734; OTTHUMP00000023735; OTTHUMP00000023736; brain-expressed X-linked protein 2;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
MYC
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	BEX2-8463HCL	Recombinant Human BEX2 293 Cell Lysate	HEK293	N/A	Inquiry
Human	BEX2-2596H	Recombinant Human BEX2 Protein, His-tagged	E.coli	His	Inquiry
Mouse	Bex2-704M	Recombinant Mouse Bex2 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK	Inquiry
Rat	BEX2-972R	Recombinant Rat BEX2 Protein	Mammalian Cell	His	Inquiry
Rat	BEX2-630R	Recombinant Rat BEX2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	BEX2-630R-B	Recombinant Rat BEX2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

BEX2 involved in several pathways and played different roles in them. We selected most pathways BEX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BEX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

BEX2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BEX2 itself. We selected most functions BEX2 had, and list some proteins which have the same functions with BEX2. You can find most of the proteins on our site.

Function	Related Protein
protein binding	SOST;DAZAP2;ILKAP;CDH1;DPH1;RNF34;HNF4A;ARNTL2;BNIPL

BEX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BEX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BEX2.

TRIM42; FSD2; NECAB2; KRT38; TRIM27; KRT15; KRTAP5-9