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BMP8B

  • Official Full Name

    bone morphogenetic protein 8b

  • Overview

    The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.
  • Synonyms

    BMP8B; bone morphogenetic protein 8b; BMP8, bone morphogenetic protein 8 (osteogenic protein 2); OP 2; osteogenic protein 2; BMP-8; BMP-8B; BMP8B_HUMAN; Bone morphogenetic protein 8; OP-2; OP2; OTTHUMP00000010836; bone morphogenetic protein 8 (osteogenic protein 2); dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); BMP8;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • CHO
  • E. coli
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • His(N
  • ter)
  • His|SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BMP8B-230H Active Recombinant Human BMP8B protein CHO N/A
Human BMP8B-018H Active Recombinant Human BMP8B Protein E. coli
Human BMP8B-18H Recombinant Human BMP8B, His-tagged E.coli His
Human BMP8B-27490TH Recombinant Human BMP8B Wheat Germ N/A 89 amino acids
Human BMP8B-250H Recombinant Human BMP8B, His-tagged E.coli His 264-402aa
Human BMP8B-8428HCL Recombinant Human BMP8B 293 Cell Lysate HEK293 N/A
Human BMP8B-0774H Recombinant Human BMP8B Protein (Thr261-Cys399), N-His tagged E.coli N-His Thr261-Cys399
Human BMP8B-19H Recombinant Active Human BMP8B Protein, His-tagged(N-ter) E.coli His(N-ter)
Human BMP8B-283H Active Recombinant Human BMP8B Protein (Ala264-His402), N-His tagged, Animal-free, Carrier-free E.coli N-His Ala264-His402
Mouse BMP8B-2436M Recombinant Mouse BMP8B Protein Mammalian Cell His
Mouse BMP8B-2692M Recombinant Mouse BMP8B Protein (261-399 aa), His-SUMO-tagged E.coli His/SUMO 261-399 aa
Mouse BMP8B-1056M-B Recombinant Mouse BMP8B Protein Pre-coupled Magnetic Beads HEK293
Mouse BMP8B-1056M Recombinant Mouse BMP8B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BMP8B Related Gene Family
  • BMP8B Related Research Area

BMP8B involved in several pathways and played different roles in them. We selected most pathways BMP8B participated on our site, such as TGF-beta signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP8B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
TGF-beta signaling pathwayACVR2A;NODAL;ID3;TGFB1;SMAD7;TFDP1;SMAD4;TGFBR1A;SMAD9
Hippo signaling pathwayFZD7;ACTG1;FZD9;APC;Fzd4;SAV1;PRKCZ;LLGL1;PPP2CB

BMP8B has several biochemical functions, for example, BMP receptor binding, cytokine activity, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP8B itself. We selected most functions BMP8B had, and list some proteins which have the same functions with BMP8B. You can find most of the proteins on our site.

Function Related Protein
BMP receptor bindingBMP8A;BMP2;BMP5;BMP7A;BMP8B;BMP3;BMP4;BMP6;BMP7B
cytokine activityGREM2;FLT3LG;IL17A/F2;CCL4;IL17A/F1;CXCL9;CMTM3;TNFSF4;CCL6
growth factor activityTGFA;THPO;CXCL12;PDGFAB;DKK1;IL10;FGF11;FGF11A;JAG1
transforming growth factor beta receptor bindingGDF9;INHBAA;GDF1;NODAL;GDF10B;MSTN;GDF2;GDF3;GDF5

BMP8B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP8B here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP8B.

WFIKKN2; WFIKKN1; ABL1; FYN

TGF
  • Q&As
  • Reviews

Q&As (5)

Ask a question
Are there any clinical implications of BMP8B in obesity treatment? 02/24/2023

Research suggests that BMP8B could be a potential target for obesity treatment due to its involvement in metabolic regulation, but more studies are needed to fully understand its therapeutic potential.

How is BMP8B linked to cardiovascular health? 11/05/2020

BMP8B has been implicated in cardiovascular health, with studies suggesting its involvement in vascular smooth muscle cell function and potential implications for cardiovascular diseases.

Does BMP8B play a role in cancer development or progression? 08/21/2020

The role of BMP8B in cancer is still under investigation. Some studies suggest it may influence cancer cell behavior, but the exact mechanisms are not fully understood.

Are there any known side effects associated with manipulating BMP8B levels? 08/28/2019

The potential side effects of manipulating BMP8B levels are not yet fully elucidated, and this is an area of active research.

How does BMP8B contribute to fertility? 12/23/2018

BMP8B has been associated with female fertility, and studies indicate its involvement in the regulation of ovulation and the menstrual cycle.

Customer Reviews (3)

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Reviews
07/06/2021

    The knowledgeable and responsive support team is dedicated to resolving issues and providing solutions that are tailored to specific experimental requirements.

    09/16/2019

      This enables researchers to confidently incorporate BMP8B into their studies, knowing that they have access to a reliable and well-characterized protein that will contribute to robust and accurate results.

      04/09/2016

        the high-quality BMP8B protein is available in various forms, including recombinant proteins and purified samples, enabling researchers to select the most suitable format for their specific experimental setup.

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