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BNIP3

  • Official Full Name

    BCL2/adenovirus E1B interacting protein 3

  • Overview

    BNIP3 (Bcl-2/E1B-19kDa interacting protein 3) is a pro-apoptotic mitochondrial protein and Bcl-2 family member that contains a Bcl-2 homology 3 (BH3) domain and a carboxyl terminal transmembrane (TM) domain. While BNIP3 has a predicted molecular weight of
  • Synonyms

    BNIP3; BCL2/adenovirus E1B interacting protein 3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BCL2/adenovirus E1B interacting protein 1, NIP3; BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3; BCL2/adenovirus E1B 19 kDa-interacting prot;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Zebrafish
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • In vitro E. coli expression system
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BNIP3-10262H Recombinant Human BNIP3, His-tagged E.coli His 68-121a.a.
Human BNIP3-809H Recombinant Human BNIP3 Protein, His-tagged E.coli His
Human BNIP3-294H Recombinant Human BNIP3 Protein, GST-tagged Wheat Germ GST
Human BNIP3-8423HCL Recombinant Human BNIP3 293 Cell Lysate HEK293 N/A
Human BNIP3-810H Recombinant Human BNIP3, GST-tagged E. coli GST 68-121 aa
Human BNIP3-3759HF Recombinant Full Length Human BNIP3 Protein, GST-tagged In Vitro Cell Free System GST 194 amino acids
Mouse BNIP3-2448M Recombinant Mouse BNIP3 Protein Mammalian Cell His
Mouse BNIP3-1062M Recombinant Mouse BNIP3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse BNIP3-2403M Recombinant Mouse BNIP3 Protein (1-156 aa), His-tagged E.coli His 1-156 aa
Mouse BNIP3-1062M-B Recombinant Mouse BNIP3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Bnip3-2354M Recombinant Mouse Bnip3 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 1-187aa
Mouse Bnip3-2355M Recombinant Mouse Bnip3 Transmembrane protein, His-tagged In vitro E. coli expression system His 50-187aa
Rat Bnip3-1684R Recombinant Rat Bnip3 protein, His & GST-tagged E.coli His/GST Gln3~Ala134 (Accession # Q9ET45)
Bos taurus (Bovine) RFL12145BF Recombinant Full Length Bovine Bcl2/Adenovirus E1B 19 Kda Protein-Interacting Protein 3(Bnip3) Protein, His-Tagged E.coli expression system His Full Length (1-196)
Homo sapiens (Human) RFL18293HF Recombinant Full Length Human Bcl2/Adenovirus E1B 19 Kda Protein-Interacting Protein 3(Bnip3) Protein, His-Tagged E.coli expression system His Full Length (1-194)
Mus musculus (Mouse) RFL18127MF Recombinant Full Length Mouse Bcl2/Adenovirus E1B 19 Kda Protein-Interacting Protein 3(Bnip3) Protein, His-Tagged E.coli expression system His Full Length (1-187aa)
Zebrafish BNIP3-2001Z Recombinant Zebrafish BNIP3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BNIP3 Related Articles
  • BNIP3 Related Research Area

BNIP3 involved in several pathways and played different roles in them. We selected most pathways BNIP3 participated on our site, such as FoxO signaling pathway, Legionellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BNIP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
FoxO signaling pathwaySMAD2;INSB;INS2;CCND2;PRKAA1;MAPK10;BNIP4;MAPK13;INSRA
LegionellosisCASP9;HSPD1;RAB1A;CR1;HSPA8;HSPA1A;IL12A;IL12B;NLRC4

BNIP3 has several biochemical functions, for example, GTPase binding, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BNIP3 itself. We selected most functions BNIP3 had, and list some proteins which have the same functions with BNIP3. You can find most of the proteins on our site.

Function Related Protein
GTPase bindingSTOML2;RASA1;ENO1;SPTBN1;IARS;LCP1;MARCH5;SH3GL1;RAB3D
identical protein bindingSH3BP4;USP2;GCC2;DESI1;S100A4;PARK2;AXIN1;FADD;TK1
protein bindingC1QTNF6;NAV1;PPARGC1A;TEC;STK10;ERC1;FOXP3;PEX14;NOG
protein heterodimerization activityNFYBB;PRPH;SMC1A;ALX1;BCL2L10;H2BFWT;PDSS1;HIST1H2B7;H2-AB1
protein homodimerization activityEVLA;TDG;CSF1;CASQ2;P2RX4;DMRT3A;PKD2;PRMT2;XPNPEP1

BNIP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BNIP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of BNIP3.

BNIP3L; TMEM11

Zhang, XS; Bian, XW; et al. The Proapoptotic Protein BNIP3 Interacts with VDAC to Induce Mitochondrial Release of Endonuclease G. PLOS ONE 9:-(2014).
Awan, MUF; Hasan, M; et al. Neuroprotective role of BNIP3 under oxidative stress through autophagy in neuroblastoma cells. MOLECULAR BIOLOGY REPORTS 41:5729-5734(2014).
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