Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

BRAF

  • Official Full Name

    v-raf murine sarcoma viral oncogene homolog B1

  • Overview

    The Raf proteins are a family of serine/threonine-specific kinases that serve as a central intermediate in transmitting extracellular signals to the mitogen-activated protein kinase cascade, which controls cell growth, differentiation and survival. Three
  • Synonyms

    BRAF; v-raf murine sarcoma viral oncogene homolog B1; serine/threonine-protein kinase B-raf; BRAF1; p94; 94 kDa B-raf protein; proto-oncogene B-Raf; murine sarcoma viral (v-raf) oncogene homolog B1; B-Raf proto-oncogene serine/threonine-protein kinase (p9;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • Baculovirus-Insect cells
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Insect cells
  • Insects cell
  • Mammalian Cell
  • Mammalian cells
  • Protein Conjugation
  • Sf21 Insect Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • DDK
  • Flag
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • His|Flag
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BRAF-550H Active Recombinant Human BRAF/p50 Protein, Flag-His-tagged Insects cell His/Flag
Human BRAF-791H Active Recombinant Human BRAF protein, GST-tagged Insect Cell GST
Human BRAF-22H Active Recombinant Human BRAF protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BRAF-319H Active Recombinant Human BRAF Protein, GST-His-tagged Sf9 Insect Cell GST/His
Human BRAF-321H Active Recombinant Human BRAF Protein, GST-tagged Wheat Germ GST
Human BRAF-179H Recombinant Human BRAF protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BRAF-26566TH Recombinant Human BRAF N/A
Human BRAF-176H Recombinant Human BRAF protein, DDK-tagged HEK293 DDK
Human BRAF-320H Recombinant Human BRAF Protein, GST-tagged Sf21 Insect Cell GST
Human BRAF-180H Recombinant Human BRAF protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BRAF-175H Recombinant Human BRAF protein, DDK-tagged HEK293 DDK Asp380-His766
Human BRAF-178H Recombinant Human BRAF protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BRAF-994H Recombinant Human V-Raf Murine Sarcoma Viral Oncogene Homolog B1, GST-tagged Sf9 Insect Cell GST
Human BRAF-181H Recombinant Human BRAF protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BRAF-177H Recombinant Human BRAF protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BRAF-183H Recombinant Human BRAF protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BRAF-174H Recombinant Human BRAF protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BRAF-182H Recombinant Human BRAF protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BRAF-26567TH Recombinant Human BRAF N/A
Human BRAF-253H Recombinant Human BRAF, GST-tagged, Active Sf9 Insect Cell GST
Human BRAF-8414HCL Recombinant Human BRAF 293 Cell Lysate HEK293 N/A
Human BRAF-12HFL Recombinant Human BRAF Protein, Full Length, GST tagged Insect cells GST Full Length
Human BRAF-456H-B Recombinant Human BRAF Protein Pre-coupled Magnetic Beads HEK293
Human BRAF-328H Recombinant Human BRAF Protein, His-tagged E.coli N-His Ile457-Leu717
Human BRAF-456H Recombinant Human BRAF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human BRAF-2781H Recombinant Human BRAF Protein, His-tagged, BSA Conjugated Protein Conjugation N-His C+Thr8-Trp23
Human BRAF-1391H Recombinant Human BRAF Protein (500-766), His tagged E.coli His 500-766
Human BRAF-2782H Recombinant Human BRAF Protein, His-tagged, BSA Conjugated Protein Conjugation N-His Arg726-Ala736+C
Human BRAF-68HFL Recombinant Full Length Human BRAF Protein, C-Flag-tagged Mammalian cells Flag
Human BRAF-0217H Recombinant Human BRAF Protein (Full Length), N-His-tagged Baculovirus-Insect cells N-His Full Length
Human BRAF-0787H Recombinant Human BRAF Protein (Asn500-His766), N-His tagged E.coli N-His Asn500-His766
Mouse BRAF-2477M Recombinant Mouse BRAF Protein Mammalian Cell His
Mouse BRAF-1081M Recombinant Mouse BRAF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse BRAF-1081M-B Recombinant Mouse BRAF Protein Pre-coupled Magnetic Beads HEK293
Mouse Braf-441M Recombinant Mouse Braf Protein, MYC/DDK-tagged HEK293T MYC/DDK
Zebrafish BRAF-11759Z Recombinant Zebrafish BRAF Mammalian Cell His
Chicken BRAF-6854C Recombinant Chicken BRAF Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BRAF Related Articles
  • BRAF Related Research Area

BRAF involved in several pathways and played different roles in them. We selected most pathways BRAF participated on our site, such as MAPK signaling pathway, ErbB signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRAF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayPPP3R2;CACNG7A;MEF2C;FGFR1;MAP4K2;PPM1BA;PRKACAA;PRKACG;CACNB3
ErbB signaling pathwayERBB4A;GSK3B;SHC1;ERBB3A;PIK3R3;ERBB2;PAK7;MYCB;PRKCA
Rap signaling pathwayDOCK4;Itgam&Itgb2;HRAS;PDGFC;INSR;AKT2;FGF2;FGF14;PIK3R3
cAMP signaling pathwayPDE4A;SLC9A1;MC2R;RAC3;PTCH1;ATP1A2;NFKB1;PTGER2;CREB3L1
Chemokine signaling pathwayPIK3CA;VAV1;CCL2;CXCL11;GNB3;CCL21;PRKCB;AKT2;CCL11
FoxO signaling pathwayMAPK14A;SMAD3;BNIP3;FASLG;PIK3R5;INSR;MAPK12B;NRAS;IKBKB
mTOR signaling pathwayRHEB;RRN3;ULK1;AKT1S1;IKBKB;PTENA;PRKCB;TSC1A;STRADA
Vascular smooth muscle contractionCALD1B;CYP4A14;AGTR1A;PLA2G5;CALM3B;GUCY1B3;CALM1;KCNMB3;KCNMB4
Focal adhesionRHOAA;LAMB4;BCL2;THBS4A;DIAPH1;GRB2;ACTN3;LAMA1;ACTN1
Natural killer cell mediated cytotoxicityKIR3DL2;FCGR3A;KIR2DS5;FAS;RAC2;IFNA8;IFNA21;PIK3CD;MICA
Long-term potentiationCALM3;ATF4;PPP1CC;KRAS;GRIN2B;GNAQ;RAF1;PPP3R2;ITPR3
Neurotrophin signaling pathwayMAPK8;SHC4;MAP2K1;FASLG;NRAS;MAP3K3;PTPN11;NGF;NFKB1
Serotonergic synapseSLC18A2;PLA2G4D;ALOX12B;PLA2G4A;GNAI1;GNG13;KCND2;PLCB2;HTR3E
Long-term depressionGNAQ;GRIA2;GRIA1;ITPR3;RAF1;PRKG2;PPP2CB;PPP2CA;PPP2R1B
Regulation of actin cytoskeletonITGA1;RRAS;VAV1;FGF17;Pdgfa&Pdgfb;ITGB7;CFL2;MSNB;PIP4K2A
Insulin signaling pathwayINS;PCK2;PHKG2;FBP1A;PRKACBA;GYS2;PIK3R3A;INSRA;PPP1CBL
Progesterone-mediated oocyte maturationSPDYA;IGF1R;BUB1;CPEB3;ANAPC2;IGF1RB;CDC27;GNAI1;RAF1A
AlcoholismATF6B;HIST1H4F;GM14483;HIST3H2BB;PPP1CB;GM14476;HIST1H4A;HIST2H3C2;HIST1H2AN
Hepatitis CPIK3R5;RNASEL;CLDN6;PPP2R2D;CLDN5;TRAF2;CLDN9;PPP2CB;MAPK10
Pathways in cancerTRAF3;KIT;MSH2;EGLN1;LAMC2;CSF3R;GNAQ;IKBKG;FZD7
Proteoglycans in cancerMTOR;PLCG1;PRKCA;ROCK2;DROSHA;PLAU;FZD5;WNT2B;CBL
Colorectal cancerAPC;LEF1;MAPK1;Casp3;RALGDS;TCF7L2;TCF7;PIK3R3;SMAD2
Renal cell carcinomaMAP2K1;FLCN;BRAF;SLC2A1;ETS1;MAPK1;PIK3CB;AKT1;PIK3CD
Pancreatic cancerTGFBR2;TRP53;BRAF;ERBB2;RAC1;MAPK3;RAF1;RALB;BAD
Endometrial cancerAXIN1;MLH1;MAP2K2;ERBB2;PIK3R3;KRAS;CTNNA2;PIK3CD;BAD
GliomaPIK3R5;MAPK3;CAMK2D;PRKCA;RB1;CALM4;IGF1;TGFA;KRAS
Prostate cancerTCF7L2;NKX3-1;GRB2;INSRR;SRD5A2;Pdgfa&Pdgfb;ACTL6B;BAD;PIK3CD
Thyroid cancerMAP2K2;MAP2K1;TCF7L2;KRAS;TCF7;RXRA;TRP53;NCOA4;CCDC6
MelanomaFGF2;PIK3R3;AKT1;PIK3CA;BAD;TP53;FGF18;MAPK1;PIK3CG
Bladder cancerTRP53;DAPK2;ARAF;MMP9;TYMP;ERBB2;TP53;FGFR3;MAPK1
Chronic myeloid leukemiaMAP2K1;MAPK1;CRKL;HDAC1;RAF1;PIK3R5;BCR;CBL;SHC2
Acute myeloid leukemiaKIT;MTOR;RELA;PIK3CB;TCF7;RUNX1;RUNX1T1;CCND1;CEBPA
Non-small cell lung cancerFOXO3;RAF1;TRP53;RASSF5;MAPK3;FHIT;PLCG2;AKT2;STK4

BRAF has several biochemical functions, for example, ATP binding, MAP kinase kinase kinase activity, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRAF itself. We selected most functions BRAF had, and list some proteins which have the same functions with BRAF. You can find most of the proteins on our site.

Function Related Protein
ATP bindingRAD50;TTN;PLK2;PAK2B;ERN2;ABCA1B;TLK1A;P2RX3;CSF1R
MAP kinase kinase kinase activityMAP3K5;KIAA1804;MAP3K3;MAP3K1;MAP3K2;ZAK;MAP3K6;BRAF;ALPK2
calcium ion bindingTPD52;SYT11;PCDH2AB1;CALR3;Shh;EDEM2;PCDH2G8;EFCAB5;CANT1B
identical protein bindingSNCAIP;NCAM1;CLDN11;ACADM;ERBB2;CLPP;AHI1;SCHIP1;CHAF1A
mitogen-activated protein kinase kinase bindingMAPK8IP3;TAOK2;PIN1;KSR1;TRIB1;DLG1;BRAF;TRIB3;IGBP1
protein bindingALDH3B1;PTPRE;CDON;ADAMTSL5;UBA52;FBXO28;RELA;LRP2BP;CARD11
protein heterodimerization activityTAP1;PIK3R2;TAF9B;HER1;HIST1H2A9;HIST1H2BP;PDGFB;MTTP;SLC51A
protein kinase activitySIK2A;PLK2B;BMPR1BB;CSNK1E;GM7168;EPHA4A;MAP4K3;CDK11A;RPS6KA3A
protein serine/threonine kinase activityCDK11A;ILK;ACVR2AA;ULK4;OXSR1A;SQSTM1;ULK1;VRK1;KSR2
NOT small GTPase bindingBRAF;RAF1

BRAF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRAF here. Most of them are supplied by our site. Hope this information will be useful for your research of BRAF.

MAP2K1

Johnson, DB; Peng, CW; et al. Nivolumab in melanoma: latest evidence and clinical potential. THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY 7:97-106(2015).
Bellizzi, AM; et al. Screening for Lynch Syndrome: A No-Brainer BRAF V600E Mutation-Specific Immunohistochemistry: Caveat Emptor. AMERICAN JOURNAL OF CLINICAL PATHOLOGY 143:320-324(2015).
  • Q&As
  • Reviews

Q&As (1)

Ask a question
Please let us confirm whether or not the following kinase products marketed by your company are products applicable to the Cartagena Law in Japan.
If the product is used in Japan and falls under the Cartagena Law, it needs to be controlled appropriately.
BRAF-550H 04/15/2023

This protein is not a living modified organism, so it does not apply to the Cartagena Law in Japan. No worries.

Customer Reviews (0)

Write a review

Ask a Question for All BRAF Products

Required fields are marked with *

My Review for All BRAF Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends