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BRAT1

  • Official Full Name

    BRCA1-associated ATM activator 1

  • Overview

    The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
  • Synonyms

    BRAT1; BRCA1-associated ATM activator 1; BAAT1; RMFSL; C7orf27; HEAT repeat-containing protein C7orf27; BRCA1-associated protein required for ATM activation protein 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BRAT1-0139H Recombinant Human BRAT1 Protein, GST-Tagged Wheat Germ GST
Human BRAT1-255HCL Recombinant Human BRAT1 cell lysate N/A
Human BR1-2783H Recombinant Human BRat 1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human BRAT1-5239H Recombinant Human BRAT1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human BRAT1-2610HF Recombinant Full Length Human BRAT1 Protein, GST-tagged In Vitro Cell Free System GST 821 amino acids
Mouse Brat1-1813M Recombinant Mouse Brat1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish BRAT1-3744Z Recombinant Zebrafish BRAT1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

BRAT1 involved in several pathways and played different roles in them. We selected most pathways BRAT1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with BRAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

BRAT1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRAT1 itself. We selected most functions BRAT1 had, and list some proteins which have the same functions with BRAT1. You can find most of the proteins on our site.

Function Related Protein
protein bindingCDCA8;KCNE2;PRKCI;ING2;SMPDL3A;CBX8;MAP3K7IP3;MAMSTR;PPP2R5D

BRAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRAT1.

BRCA1; ATM; NCBP1; Nipbl; PHF8

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