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BRE

Official Full Name

brain and reproductive organ-expressed (TNFRSF1A modulator)
Overview

BRCA1-A complex subunit BRE is a protein that in humans is encoded by the BRE gene.
Synonyms

BRE; brain and reproductive organ-expressed (TNFRSF1A modulator); BRCA1-A complex subunit BRE; BRCA1/BRCA2 containing complex; subunit 4; BRCC4; BRCC45; BRCA1/BRCA2-containing complex subunit 45; BRCA1/BRCA2-containing complex, subunit 4; brain and reprod;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rat
Zebrafish

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	BRE-335H	Recombinant Human BRE Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	BRE-8409HCL	Recombinant Human BRE 293 Cell Lysate	HEK293	N/A		Inquiry
Human	BRE-3787HF	Recombinant Full Length Human BRE Protein, GST-tagged	In Vitro Cell Free System	GST	415 amino acids	Inquiry
Rat	BRE-1013R	Recombinant Rat BRE Protein	Mammalian Cell	His		Inquiry
Rat	BRE-671R	Recombinant Rat BRE Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	BRE-671R-B	Recombinant Rat BRE Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	BRE-2520Z	Recombinant Zebrafish BRE	Mammalian Cell	His		Inquiry
Chicken	BRE-1836C	Recombinant Chicken BRE	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
BRE Related Articles

BRE involved in several pathways and played different roles in them. We selected most pathways BRE participated on our site, such as Cell Cycle, Cell Cycle Checkpoints, DNA Double Strand Break Response, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cell Cycle	CCND2A;CDKN1B;E2F5;ACTR1A;CEP76;DCTN1;RBL2;MSH4;NCAPH
Cell Cycle Checkpoints	CDKN1B;RAD9B;MCM10;RNF168;CDK2;BABAM1;HUS1;CDK5RAP2;HIST4H4
DNA Double Strand Break Response	UBE2V2;EYA3;CHEK2;TP53BP1;BAZ1B;KDM4A;BARD1;SMARCA5;BRCC3
DNA Double-Strand Break Repair	SMARCA5;UIMC1;TDP2B;UBE2V2;DNA2;HUS1;RAD17;EYA2;POLD3
DNA Repair	ALKBH3;PPP4R2B;USP10;SMARCA5;COPS2;RAD9;TDP2;PARP1;UBE2L6
G2/M Checkpoints	BRE;FAM175A;RAD17;TP53BP1;UIMC1;RAD9B;RAD9;HUS1;BABAM1
G2/M DNA damage checkpoint	BARD1;UIMC1;TP53BP1;BRE;BABAM1;RNF168;BRCC3;THRSP;FAM175A
HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)	WRN;GEN1;PPP4CB;RTEL1;PPP4R2A;RAD1;RBBP8;FUZ;RNF168

BRE has several biochemical functions, for example, peroxisome targeting sequence binding, polyubiquitin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRE itself. We selected most functions BRE had, and list some proteins which have the same functions with BRE. You can find most of the proteins on our site.

Function	Related Protein
peroxisome targeting sequence binding	PEX5L;PEX5;BRE
polyubiquitin binding	BAG6;VCP;AGL;SHARPIN;BRCC3;UBXN1;BRE;RAD23B;DZIP3
protein binding	DDC;ISL1;BAIAP2;ARMC2;MAP6;DAK;LTF;CCNF;PPP3CA
tumor necrosis factor receptor binding	EDA;FASLG;TNFSF9;CASP8;LTA;Fasl;TNFSF11;TNFSF10;TRAF2

BRE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRE here. Most of them are supplied by our site. Hope this information will be useful for your research of BRE.

BABAM1; BRCC3; FAM175B; RPN2; SHMT2; PHB; LRPPRC; CUL1; FKBP8; ATG2A; DHRS7B; FAM175A; USP7; TTC28

Karamitopoulou, E; Zlobec, I; et al. Proposal for a 10-high-power-fields scoring rnethod for the assessment of tumor budding in colorectal cancer. MODERN PATHOLOGY 26:295-301(2013).

Lang, LX; Li, WH; et al. New Methods for Labeling RGD Peptides with Bromine-76. THERANOSTICS 1:341-353(2011).