BUB1B
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Official Full Name
budding uninhibited by benzimidazoles 1 homolog beta
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Overview
The Mitotic Checkpoint Complex (MCC), which contains Bub1, Bub1b, Bub3, Mad2, and Cdc20, controls chromosome segregation and monitors kinetochore-microtubule interactions (1). During mitosis, the MCC complex inhibits the ubiquitin ligase activity of the A -
Synonyms
BUB1B; budding uninhibited; budding uninhibited by benzimidazoles 1 (yeast homolog), beta; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; Bub1A; BUBR1; MAD3L; SSK1; mitotic checkpoint kinase MAD3L; MAD3/BUB1-related protein kinase; hBUBR1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Chicken
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect (sf21)
- Mammalian Cell
- Sf9 Insect Cell
- Wheat Germ
- GST
- His
- Myc
- DDK
- MYC
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | BUB1B-1371H | Active Recombinant Human BUB1B, GST-tagged | Sf9 Insect Cell | GST | 613 aa-end |
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| Human | BUB1B-26124TH | Recombinant Human BUB1B | Wheat Germ | N/A | 130 amino acids |
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| Human | BUB1B-10335H | Recombinant Human BUB1B, GST-tagged | E.coli | GST | C-term-333a.a. | |
| Human | BUB1B-27105TH | Recombinant Human BUB1B | Wheat Germ | N/A | 1050 amino acids |
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| Human | BUB1B-8382HCL | Recombinant Human BUB1B 293 Cell Lysate | HEK293 | N/A |
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| Human | BUB1B-465H | Recombinant Human BUB1B Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Human | BUB1B-4915HF | Active Recombinant Full Length Human BUB1B Protein, GST-tagged | Insect (sf21) | GST | 1-1050(end) |
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| Human | BUB1B-59HF | Recombinant Full Length Human BUB1B Protein | In Vitro Cell Free System | 1050 amino acids |
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| Mouse | Bub1b-726M | Recombinant Mouse Bub1b Protein, MYC/DDK-tagged | HEK293T | MYC/DDK |
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| Chicken | BUB1B-5973C | Recombinant Chicken BUB1B | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
BUB1B involved in several pathways and played different roles in them. We selected most pathways BUB1B participated on our site, such as Cell cycle, HTLV-I infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with BUB1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | GINS3;ATM;SMC1B;CEP63;CCNB1;AURKB;THRSP;RAD1;TMEM188 |
| HTLV-I infection | WNT2;IL2RA;HLA-DPA1;BUB3;TERT;BUB1B;TNF;VDAC3;FZD5 |
BUB1B has several biochemical functions, for example, ATP binding, protein binding, protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BUB1B itself. We selected most functions BUB1B had, and list some proteins which have the same functions with BUB1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | ATP5B;ACSF3;MYO1D;IP6K2;PARS2;SKIV2L;GLYCTK;ACLYA;STK17B |
| protein binding | CHCHD2;TYRO3;HSPH1;OCA2;COQ9;TCOF1;C3orf62;PPFIA2;MAB21L1 |
| protein kinase activity | VRK1;CAMK2B1;EPHB4B;INSRB;CDKL2;SCYL2;ANKK1;ACVR1L;PRKCA |
| protein serine/threonine kinase activity | PAK6;CHEK1;WNK2;PRKG1A;PRKCDA;STK32B;TAOK3;EIF2AK4;ADCK1 |
BUB1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BUB1B here. Most of them are supplied by our site. Hope this information will be useful for your research of BUB1B.
CDC20; BUB3
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