C
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Official Full Name
chib
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Overview
Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
C; chib; C22orf2, chromosome 22 open reading frame 2 , PGEA1, PKD2 interactor, golgi and endoplasmic reticulum associated 1; protein chibby homolog 1; Cby; Chibby; PIGEA 14; PIGEA14; C22orf2; Cytosolic leucine rich protein; HRIHFB2025; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; Protein Chibby; OTTHUMP00000198875; OTTHUMP00000198876; OTTHUMP00000198878; ARPP-binding protein; coiled-coil protein PIGEA-14; cytosolic leucine-rich protein; PKD2 interactor, golgi and end; arb1; PGEA1; PIGEA-14; HS508I15A;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Dengue
- DENV
- HBV
- HBV-D ayw (isolate France/Tiollais/1979)
- HCV
- Human
- JEV
- Measles Virus
- Mouse
- Rat
- Rubella Virus
- RuV
- SARS
- Streptomyces phage phiC31
- YEV
- CHO
- E. coli or Yeast
- E.coli
- HEK293
- Insect Cell
- Mammalian Cell
- P.pastoris
- C
- His
- Fc
- GST
- hIgG
- His (Fc)
- Avi
- N/A
- N
- FLAG
- SUMO
- Involved Pathway
- Protein Function
- Interacting Protein
- C Related Articles
- C Related Gene Family
C involved in several pathways and played different roles in them. We selected most pathways C participated on our site, such as Deactivation of the beta-catenin transactivating complex, Signal Transduction, Signaling by Wnt, which may be useful for your reference. Also, other proteins which involved in the same pathway with C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Deactivation of the beta-catenin transactivating complex | SOX6;BCL9;BCL9L;TLE3;RBBP5;SOX7;TLE1;TLE3B;SOX9B |
| Signal Transduction | KEL;ARHGAP29;ARHGAP17A;RLN3;ARHGAP29B;FABP11A;CDC42EP1B;RNF31;SOX4A |
| Signaling by Wnt | PRICKLE1B;BCL9L;KREMEN2;RSPO2;WIF1;FAM123B;ROR1;HECW1;TMED5 |
| TCF dependent signaling in response to WNT | SOX4B;BCL9;CDC73;RYK;SOX4A;C;LGR5;LGR6;LEO1 |
C has several biochemical functions, for example, beta-catenin binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C itself. We selected most functions C had, and list some proteins which have the same functions with C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-catenin binding | DACT2;TCF7L1A;TBL1X;SMAD7;TAX1BP3;PTPRU;HDAC6;KLF4;APC |
| identical protein binding | IFIT3;TRIM55;DYNLT1A;SLC22A1;STAT2;BAK1;HSPB1;DYNLRB1;CSK |
C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C here. Most of them are supplied by our site. Hope this information will be useful for your research of C.
Hmga2
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