C1GALT1C1
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Official Full Name
C1GALT1-specific chaperone 1
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Overview
This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. -
Synonyms
C1GALT1C1; C1GALT1-specific chaperone 1; C1GALT2; COSMC; HSPC067; MGC19947; Beta 1,3 galactosyltransferase 2; Beta1,3 galactosyltransferase 2; C1Gal T2; C1GALT1 specific chaperone 1; C38H2 L1; C38H2 like protein 1; C38H2L1; Core 1 beta3 galactosyltransferase specific molecular chaperone; Core 1 UDP galactose:N acetylgalactosamine alpha R beta 1,3 galactosyltransferase 2; MST143; C1Gal-T2; core 1 beta3-Gal-T2; C38H2-like protein 1; beta 1,3-galactosyltransferase 2; core 1 beta1,3-galactosyltransferase 2; core 1 beta3-galactosyltransferase-specific molecular chaperone; C38H2-L1;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- C1GALT1C1 Related Articles
C1GALT1C1 involved in several pathways and played different roles in them. We selected most pathways C1GALT1C1 participated on our site, such as Mucin type O-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with C1GALT1C1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mucin type O-Glycan biosynthesis | GCNT1;C1GALT1;GALNTL1;GALNTL2;C1GALT1A;GALNT6;C1GALT1B;GALNT3;ST6GALNAC1 |
| Metabolic pathways | ABO;GALNT1;PISD;TK1;RDH8;CD38;DAO.1;POLR3A;HGSNAT |
C1GALT1C1 has several biochemical functions, for example, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity, polypeptide N-acetylgalactosaminyltransferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C1GALT1C1 itself. We selected most functions C1GALT1C1 had, and list some proteins which have the same functions with C1GALT1C1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity | C1GALT1A;C1GALT1;C1GALT1B;C1GALT1C1 |
| polypeptide N-acetylgalactosaminyltransferase activity | GALNTL4;GALNT2;GALNT1;GALNTL1;GALNT10;GALNT3;GALNTL2;GALNT9;GALNTL6 |
| protein binding | POLR2J;TTR;KCNIP2;AKT2;USP44;RPS25;ICAM5;OXR1;APOBEC1 |
C1GALT1C1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C1GALT1C1 here. Most of them are supplied by our site. Hope this information will be useful for your research of C1GALT1C1.
C1GALT1; ymfN; RNF41
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