CABP1
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Official Full Name
calcium binding protein 1
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Overview
The product of this gene belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Expression of this gene was only detected in retina and brain. Study of the mouse homolog demonstrated that groups of cells expressing this protein are located in the center or inner border of the inner unclear layer of retina. Three alternatively spliced variants encoding different isoforms have been described. -
Synonyms
CABP1; calcium binding protein 1; calcium-binding protein 1; calbrain; caldendrin; CABP 1; CABP1_HUMAN; Calcium binding protein 5; HCALB BR; HCALB_BR; OTTHUMP00000210617; OTTHUMP00000210618; OTTHUMP00000210619; OTTHUMP00000210620;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- Myc|DDK
- Involved Pathway
- Protein Function
- Interacting Protein
- CABP1 Related Articles
CABP1 involved in several pathways and played different roles in them. We selected most pathways CABP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CABP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
CABP1 has several biochemical functions, for example, calcium ion binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CABP1 itself. We selected most functions CABP1 had, and list some proteins which have the same functions with CABP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | PCDHA6;PLA2G4A;PLA2G12A;CRACR2B;CAPN1B;CDH19;GRIN1;OTOFA;PGS1 |
| metal ion binding | TRPM6;PFKP;B3GAT1;ZNF785;TESK1;FDX1L;FOXP2;ZNF232;ZBBX |
| protein binding | ADNP;HSD17B10;ARL13B;F8;SETD6;COMMD5;KRTAP3-1;WDR61;NCAPH2 |
CABP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CABP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CABP1.
- Q&As
- Reviews
Q&As (7)
Ask a questionDysregulation of CABP1 might impact neural function and has potential implications in neurological disorders or calcium homeostasis-related conditions.
Possible post-translational modifications like phosphorylation can be explored using mass spectrometry or targeted biochemical assays.
CABP1 is primarily expressed in the nervous system, especially in neurons, but might also be found in other tissues.
By binding calcium and interacting with calcium channels, CABP1 can modulate calcium influx and, consequently, calcium-dependent signaling pathways.
CABP1 plays a role in modulating calcium-mediated cellular signaling by binding to calcium ions and interacting with calcium channels.
CABP1 interacts with specific voltage-gated calcium channels, influencing their activity.
Mutations might affect CABP1's calcium-binding sites, leading to altered calcium binding affinity and, thus, modulating its regulatory role.
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